Topology optimization of passive cell traps

doi:10.3390/mi12070809

CORC > 长春光学精密机械与物理研究所 > 中国科学院长春光学精密机械与物理研究所

	Topology optimization of passive cell traps
	Z. Wang; Y. Guo; E. Wadbro and Z. Liu
刊名	Micromachines
	2021
卷号	12 期号:7
ISSN号	2072666X
DOI	10.3390/mi12070809
英文摘要	This paper discusses a flexible design method of cell traps based on the topology optimization of fluidic flows. Being different from the traditional method, this method obtains the periodic layout of the cell traps according to the cell trapping requirements by proposing a topology optimization model. Additionally, it satisfies the cell trapping function by restricting the flow distribution while taking into account the overall energy dissipation of the flow field. The dependence on the experience of the designer is reduced when this method is used to design a cell trap with acceptable trapping performance. By comparing the influence of the changes of various parameters on the optimization results, the flexibility of the topology optimization method for cell trap structure optimization is verified. The capability of this design method is validated by several performed comparisons between the obtained layouts and optimized designs in the published literature. 2021 by the authors. Licensee MDPI, Basel, Switzerland.
URL标识	查看原文
内容类型	期刊论文
源URL	[http://ir.ciomp.ac.cn/handle/181722/65705]
专题	中国科学院长春光学精密机械与物理研究所
推荐引用方式 GB/T 7714	Z. Wang,Y. Guo,E. Wadbro and Z. Liu. Topology optimization of passive cell traps[J]. Micromachines,2021,12(7).
APA	Z. Wang,Y. Guo,&E. Wadbro and Z. Liu.(2021).Topology optimization of passive cell traps.Micromachines,12(7).
MLA	Z. Wang,et al."Topology optimization of passive cell traps".Micromachines 12.7(2021).