Structure attention co-training neural network for neovascularization segmentation in intravascular optical coherence tomography | |
Wu, Xiangjun2,3,4; Zhang, Yingqian1; Zhang, Peng5; Hui, Hui2,3,6; Jing, Jing1; Tian, Feng1; Jiang, Jingying4; Yang, Xin2,3; Chen, Yundai1,7; Tian, Jie2,3,4,8 | |
刊名 | MEDICAL PHYSICS |
2022-01-28 | |
页码 | 16 |
关键词 | co-training IVOCT neovascularization segmentation structural attention mechanism |
ISSN号 | 0094-2405 |
DOI | 10.1002/mp.15477 |
通讯作者 | Chen, Yundai(cyundai@vip.163.com) ; Tian, Jie(jie.tian@ia.ac.cn) |
英文摘要 | Purpose To development and validate a neovascularization (NV) segmentation model in intravascular optical coherence tomography (IVOCT) through deep learning methods. Methods and materials A total of 1950 2D slices of 70 IVOCT pullbacks were used in our study. We randomly selected 1273 2D slices from 44 patients as the training set, 379 2D slices from 11 patients as the validation set, and 298 2D slices from the last 15 patients as the testing set. Automatic NV segmentation is quite challenging, as it must address issues of speckle noise, shadow artifacts, high distribution variation, etc. To meet these challenges, a new deep learning-based segmentation method is developed based on a co-training architecture with an integrated structural attention mechanism. Co-training is developed to exploit the features of three consecutive slices. The structural attention mechanism comprises spatial and channel attention modules and is integrated into the co-training architecture at each up-sampling step. A cascaded fixed network is further incorporated to achieve segmentation at the image level in a coarse-to-fine manner. Results Extensive experiments were performed involving a comparison with several state-of-the-art deep learning-based segmentation methods. Moreover, the consistency of the results with those of manual segmentation was also investigated. Our proposed NV automatic segmentation method achieved the highest correlation with the manual delineation by interventional cardiologists (the Pearson correlation coefficient is 0.825). Conclusion In this work, we proposed a co-training architecture with an integrated structural attention mechanism to segment NV in IVOCT images. The good agreement between our segmentation results and manual segmentation indicates that the proposed method has great potential for application in the clinical investigation of NV-related plaque diagnosis and treatment. |
资助项目 | National Key Research and Development Program of China[2017YFA0700401] ; National Key Research and Development Program of China[2016YFC0103803] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81800221] ; National Natural Science Foundation of China[81870178] ; National Natural Science Foundation of China[81971662] ; National Natural Science Foundation of China[81671851] ; National Natural Science Foundation of China[81527805] ; CAS Youth Innovation Promotion Association[2018167] ; CAS Key Technology Talent Program ; Natural Science Foundation of Beijing City[7202105] ; Project of High-Level Talents Team Introduction in Zhuhai City[HLHPTP201703] |
WOS关键词 | ATHEROSCLEROTIC PLAQUE ; LUMEN SEGMENTATION ; VULNERABILITY ; IMPLANTATION ; NET |
WOS研究方向 | Radiology, Nuclear Medicine & Medical Imaging |
语种 | 英语 |
出版者 | WILEY |
WOS记录号 | WOS:000747983100001 |
资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China ; CAS Youth Innovation Promotion Association ; CAS Key Technology Talent Program ; Natural Science Foundation of Beijing City ; Project of High-Level Talents Team Introduction in Zhuhai City |
内容类型 | 期刊论文 |
源URL | [http://ir.ia.ac.cn/handle/173211/47307] |
专题 | 自动化研究所_中国科学院分子影像重点实验室 |
通讯作者 | Chen, Yundai; Tian, Jie |
作者单位 | 1.Peoples Liberat Army Gen Hosp, Dept Cardiol, Med Ctr 6, Beijing 100853, Peoples R China 2.Beijing Key Lab Mol Imaging, Beijing, Peoples R China 3.Inst Automat, CAS Key Lab Mol Imaging, State Key Lab Management & Control Complex Syst, Beijing, Peoples R China 4.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Sch Med & Engn, Beijing, Peoples R China 5.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Dept Biomed Engn, Beijing, Peoples R China 6.Univ Chinese Acad Sci, Beijing, Peoples R China 7.Southern Med Univ, Guangzhou, Peoples R China 8.Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Precis Med Ctr, Zhuhai, Peoples R China |
推荐引用方式 GB/T 7714 | Wu, Xiangjun,Zhang, Yingqian,Zhang, Peng,et al. Structure attention co-training neural network for neovascularization segmentation in intravascular optical coherence tomography[J]. MEDICAL PHYSICS,2022:16. |
APA | Wu, Xiangjun.,Zhang, Yingqian.,Zhang, Peng.,Hui, Hui.,Jing, Jing.,...&Tian, Jie.(2022).Structure attention co-training neural network for neovascularization segmentation in intravascular optical coherence tomography.MEDICAL PHYSICS,16. |
MLA | Wu, Xiangjun,et al."Structure attention co-training neural network for neovascularization segmentation in intravascular optical coherence tomography".MEDICAL PHYSICS (2022):16. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论