Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production

doi:10.1016/j.memsci.2021.119082

	Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production
	Li, Xianhui 1,2,3; Su, Ziran 2; Chen, Xueming 4; Luo, Jianquan 5; Pinelo, Manuel 2
刊名	JOURNAL OF MEMBRANE SCIENCE
	2021-04-01
卷号	623 页码:12
关键词	Mathematical model Enzymatic membrane reactor Oligodextran Process optimization Membrane fouling
ISSN号	0376-7388
DOI	10.1016/j.memsci.2021.119082
英文摘要	Producing oligodextran with an enzymatic membrane reactor (EMR) is a promising alternative to traditional fermentation processes due to its high efficiency and environmental compatibility. Process analysis and optimization of an EMR system used for producing oligodextran are critical to improving EMR operating stability and cost effectiveness. We herein developed a mathematical model to evaluate the effects of operating conditions and membrane properties on the reaction-separation behavior of an EMR. Our analysis shows that tailoring a membrane with large porosity and uniform pore size distribution can simultaneously improve the product quality and production efficiency. The optimal parameters of operating pressure and agitation speed for achieving high production efficiency depend on the selection of operating mode. EMR prefers higher operating pressure to increase the production efficiency under water feeding mode. However, since the membrane suffered severer fouling under substrate feeding mode, the extensive agitation is required to inhibit membrane fouling and enhance production yield. Our work paves a new avenue towards the fundamental understanding and designing of highly effective and low consumptive EMR for oligodextran production.
资助项目	European Union[713683] ; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)[GML2019ZD0403] ; Program for Guangdong Introducing Innovative and Entrepreneurial Teams[2019ZT08L213]
WOS研究方向	Engineering ; Polymer Science
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000619230200001
资助机构	European Union ; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) ; Program for Guangdong Introducing Innovative and Entrepreneurial Teams
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/43586]
专题	中国科学院过程工程研究所
通讯作者	Luo, Jianquan; Pinelo, Manuel
作者单位	1.Guangdong Univ Technol, Inst Environm & Ecol Engn, Minist Educ, Key Lab City Cluster Environm Safety & Green Dev, Guangzhou 510006, Peoples R China 2.Tech Univ Denmark, Dept Chem & Biochem Engn, Proc & Syst Engn Ctr, DK-2800 Lyngby, Denmark 3.Southern Marine Sci & Engn Guangdong Lab Guangzho, Guangzhou 511458, Peoples R China 4.Fuzhou Univ, Coll Environm & Resources, Fuzhou 350116, Fujian, Peoples R China 5.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Li, Xianhui,Su, Ziran,Chen, Xueming,et al. Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production[J]. JOURNAL OF MEMBRANE SCIENCE,2021,623:12.
APA	Li, Xianhui,Su, Ziran,Chen, Xueming,Luo, Jianquan,&Pinelo, Manuel.(2021).Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production.JOURNAL OF MEMBRANE SCIENCE,623,12.
MLA	Li, Xianhui,et al."Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production".JOURNAL OF MEMBRANE SCIENCE 623(2021):12.