Sublyratins A-O, Labdane-Type Diterpenoids from Croton sublyratus

doi:10.1021/acs.jnatprod.1c00804

	Sublyratins A-O, Labdane-Type Diterpenoids from Croton sublyratus
	Qi, Jing-Jing 1,2; Zhou, Jun-Su 1; Zhang, Yan 1; Fan, Yao-Yue 1; Zhou, Bin 1; Liu, Hong-Chun 1; Zhao, Jin-Xin 1; Yue, Jian-Min 1,2
刊名	JOURNAL OF NATURAL PRODUCTS
	2021-11-26
卷号	84 期号:11 页码:2971-2980
ISSN号	0163-3864
DOI	10.1021/acs.jnatprod.1c00804
通讯作者	Zhao, Jin-Xin(jxzhao@simm.ac.cn) ; Yue, Jian-Min(jmyue@simm.ac.cn)
英文摘要	Fifteen new labdane-type diterpenoids, sublyratins A-O (1-15), along with four known analogues (16-19) were isolated from the aerial parts of Croton sublyratus. Their structural assignments were challenging due to the stereoisomeric features evident and were achieved by analyzing comprehensively the spectroscopic data and electronic circular dichroism spectra and using X-ray crystallographic analysis. Compounds 9 and 16-18 displayed cytotoxic activity against the HL-60 cell line with IC50 values of 1.5-2.8 mu M.
资助项目	National Natural Science Foundation[81872758] ; CAMS Innovation Fund for Medical Sciences[2019-I2M-5-080] ; Shanghai RisingStar Program Foundation (SCST)[19QA1410800]
WOS关键词	DITERPENELACTONES
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000723680000022
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/299247]
专题	中国科学院上海药物研究所
通讯作者	Zhao, Jin-Xin; Yue, Jian-Min
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China
推荐引用方式 GB/T 7714	Qi, Jing-Jing,Zhou, Jun-Su,Zhang, Yan,et al. Sublyratins A-O, Labdane-Type Diterpenoids from Croton sublyratus[J]. JOURNAL OF NATURAL PRODUCTS,2021,84(11):2971-2980.
APA	Qi, Jing-Jing.,Zhou, Jun-Su.,Zhang, Yan.,Fan, Yao-Yue.,Zhou, Bin.,...&Yue, Jian-Min.(2021).Sublyratins A-O, Labdane-Type Diterpenoids from Croton sublyratus.JOURNAL OF NATURAL PRODUCTS,84(11),2971-2980.
MLA	Qi, Jing-Jing,et al."Sublyratins A-O, Labdane-Type Diterpenoids from Croton sublyratus".JOURNAL OF NATURAL PRODUCTS 84.11(2021):2971-2980.