慢性乙型肝炎患者肠道菌群与肝脏生化指标的相关性 | |
赵志方1,3,4; 秦松1,3; 王莉2; 李莉莉1,3; 刘友德2; 邓丽霞2; 邹志强2 | |
刊名 | 生物工程学报 |
2021 | |
卷号 | 37期号:1页码:301-311 |
关键词 | 慢性乙型肝炎 肠道菌群 肝脏生化指标 |
ISSN号 | 1000-3061 |
其他题名 | Correlation between gut microbiota and liver biochemical indicators in patients with chronic hepatitis B |
文献子类 | Article |
英文摘要 | Chronic hepatitis B (CHB) is a global epidemic disease caused by hepatitis B virus that can lead to hepatic failure, even liver cirrhosis and hepatocellular carcinoma. The occurrence and development of CHB are closely related to the changes in the gut microbiota communities. To explore the relationship between the structure of gut microbiota and liver biochemical indicators, 14 CHB patients (the CHB group) and 11 healthy people (the CN group) were randomly enrolled in this study. Our results demonstrate that CHB caused changes in the gut microbiota communities and biochemical indicators, such as alanine transaminase, total bilirubin and gamma glutamyl transferase. Furthermore, CHB induced imbalance of the gut microbiota. Prevotella, Blautia, Ruminococcus, Eubacterium eligens group, Bacteroides uniformis and Ruminococcus sp. 5_1_39BFAA were associated with the critical biochemical indicators and liver injury, suggesting a new approach to CHB treatment. |
语种 | 中文 |
CSCD记录号 | CSCD:6898435 |
资助机构 | 中国科学院青年创新促进会 |
内容类型 | 期刊论文 |
源URL | [http://ir.yic.ac.cn/handle/133337/30307] |
专题 | 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
作者单位 | 1.中国科学院烟台海岸带研究所,山东烟台264003; 2.山东省烟台市奇山医院,山东烟台264001; 3.中国科学院海洋大科学研究中心,山东青岛266071; 4.中国科学院大学,北京101407 |
推荐引用方式 GB/T 7714 | 赵志方,秦松,王莉,等. 慢性乙型肝炎患者肠道菌群与肝脏生化指标的相关性[J]. 生物工程学报,2021,37(1):301-311. |
APA | 赵志方.,秦松.,王莉.,李莉莉.,刘友德.,...&邹志强.(2021).慢性乙型肝炎患者肠道菌群与肝脏生化指标的相关性.生物工程学报,37(1),301-311. |
MLA | 赵志方,et al."慢性乙型肝炎患者肠道菌群与肝脏生化指标的相关性".生物工程学报 37.1(2021):301-311. |
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