Comparative genomic analyses reveal the features for adaptation to nematodes in fungi

doi:10.1093/dnares/dsx053

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	Comparative genomic analyses reveal the features for adaptation to nematodes in fungi
	Wang, Ruizhen 2; Dong, Leiming 4; He, Ran 2; Wang, Qinghua ; Chen, Yuequ 3; Qu, Liangjian ; Zhang, Yong-An
刊名	DNA RESEARCH
	2018
卷号	25 期号:3 页码:245-256
关键词	nematophagous fungi Esteya vermicola comparative genome genome feature adaptation and evolution
ISSN号	1340-2838
DOI	10.1093/dnares/dsx053
文献子类	Article
英文摘要	Nematophagous (NP) fungi are ecologically important components of the soil microbiome in natural ecosystems. Esteya vermicola (Ev) has been reported as a NP fungus with a poorly understood evolutionary history and mechanism of adaptation to parasitism. Furthermore, NP fungal genomic basis of lifestyle was still unclear. We sequenced and annotated the Ev genome (34.2 Mbp) and integrated genetic makeup and evolution of pathogenic genes to investigate NP fungi. The results revealed that NP fungi had some abundant pathogenic genes corresponding to their niche. A number of gene families involved in pathogenicity were expanded, and some pathogenic orthologous genes underwent positive selection. NP fungi with diverse morphological features exhibit similarities of evolutionary convergence in attacking nematodes, but their genetic makeup and microscopic mechanism are different. Endoparasitic NP fungi showed similarity in large number of transporters and secondary metabolite coding genes. Noteworthy, expanded families of transporters and endo-beta-glucanase implied great genetic potential of Ev in quickly perturbing nematode metabolism and parasitic behavior. These results facilitate our understanding of NP fungal genomic features for adaptation to nematodes and lay a solid theoretical foundation for further research and application.
学科主题	Genetics & Heredity
电子版国际标准刊号	1756-1663
出版地	OXFORD
WOS关键词	SUBTILISIN-LIKE PROTEASE ; PINE WOOD NEMATODE ; NEMATOPHAGOUS FUNGUS ; VIRULENCE FACTOR ; BURSAPHELENCHUS-XYLOPHILUS ; NEMATOCIDAL ACTIVITY ; BIOLOGICAL-CONTROL ; ESTEYA-VERMICOLA ; SERINE-PROTEASE ; GENE
语种	英语
出版者	OXFORD UNIV PRESS
WOS记录号	WOS:000439825000002
资助机构	Fundamental Research Funds for the Central Non-profit Research Institute of CAF of China [CAFYBB2017SZ003] ; Institute Special Fund for Basic Research, Institute of Forest Ecology, Environment, and Protection, Chinese Academy of Forestry [CAFRIFEEP201403] ; State 863 Project - Ministry of Science and Technology of the People's Republic of China [2012AA101503]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/20600]
专题	植物园
作者单位	1.Jilin Prov Acad Forestry Sci, Forestry Resources Protect Inst, Changchun 130031, Jilin, Peoples R China 2.Chinese Acad Forestry, Res Inst Forest Ecol Environm & Protect, State Forestry Adm China, Key Lab Forest Protect, Beijing 100091, Peoples R China 3.Chinese Acad Forestry, Res Inst Forestry, State Key Lab Tree Genet & Breeding, Beijing 100091, Peoples R China 4.Beijing Bot Garden, Inst Bot, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Wang, Ruizhen,Dong, Leiming,He, Ran,et al. Comparative genomic analyses reveal the features for adaptation to nematodes in fungi[J]. DNA RESEARCH,2018,25(3):245-256.
APA	Wang, Ruizhen.,Dong, Leiming.,He, Ran.,Wang, Qinghua.,Chen, Yuequ.,...&Zhang, Yong-An.(2018).Comparative genomic analyses reveal the features for adaptation to nematodes in fungi.DNA RESEARCH,25(3),245-256.
MLA	Wang, Ruizhen,et al."Comparative genomic analyses reveal the features for adaptation to nematodes in fungi".DNA RESEARCH 25.3(2018):245-256.