ANAPHASE PROMOTING COMPLEX/CYCLOSOME-mediated cyclin B1 degradation is critical for cell cycle synchronization in syncytial endosperms

doi:10.1111/jipb.12641

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	ANAPHASE PROMOTING COMPLEX/CYCLOSOME-mediated cyclin B1 degradation is critical for cell cycle synchronization in syncytial endosperms
	Guo, Lei ; Jiang, Li 2; Lu, Xiu-Li ; Liu, Chun-Ming
刊名	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
	2018
卷号	60 期号:6 页码:448-454
ISSN号	1672-9072
DOI	10.1111/jipb.12641
文献子类	Article
英文摘要	Although it is known that in most angiosperms mitosis in early endosperm development is syncytial and synchronized, it is unclear how the synchronization is regulated. We showed previously that APC11, also named ZYG1, in Arabidopsis activates zygote division by interaction and degradation of cyclin B1. Here, we report that the mutation in APC11/ZYG1 led to unsynchronized mitosis and over-accumulation of cyclin B1-GUS in the endosperm. Mutations in two other APC subunits showed similar defects. Transgenic expression of stable cyclin B1 in the endosperm also caused unsynchronized mitosis. Further, downregulation of APC11 generated multi-nucleate somatic cells with unsynchronized mitotic division. Together, our results suggest that APC/C-mediated cyclin B1 degradation is critical for cell cycle synchronization.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
电子版国际标准刊号	1744-7909
出版地	HOBOKEN
WOS关键词	FEMALE GAMETOGENESIS ; PLANT DEVELOPMENT ; ARABIDOPSIS ; EMBRYOGENESIS ; EXPRESSION ; ZYGOTE ; APC/C ; TIME
语种	英语
出版者	WILEY
WOS记录号	WOS:000434224500002
资助机构	Mechanistic dissection of plant embryo and seed development project from The National Basic Research Program, the Ministry of Science and Technology of China [2014CB943401]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/20521]
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 2.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China 3.Chinese Acad Fishery Sci, Beijing 100141, Peoples R China
推荐引用方式 GB/T 7714	Guo, Lei,Jiang, Li,Lu, Xiu-Li,et al. ANAPHASE PROMOTING COMPLEX/CYCLOSOME-mediated cyclin B1 degradation is critical for cell cycle synchronization in syncytial endosperms[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2018,60(6):448-454.
APA	Guo, Lei,Jiang, Li,Lu, Xiu-Li,&Liu, Chun-Ming.(2018).ANAPHASE PROMOTING COMPLEX/CYCLOSOME-mediated cyclin B1 degradation is critical for cell cycle synchronization in syncytial endosperms.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,60(6),448-454.
MLA	Guo, Lei,et al."ANAPHASE PROMOTING COMPLEX/CYCLOSOME-mediated cyclin B1 degradation is critical for cell cycle synchronization in syncytial endosperms".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 60.6(2018):448-454.