Biological applications of copper-containing materials

doi:10.1016/j.bioactmat.2020.09.017

CORC > 金属研究所 > 中国科学院金属研究所

	Biological applications of copper-containing materials
	Wang, Peng 1; Yuan, Yonghui 2; Xu, Ke 1; Zhong, Hongshan 1; Yang, Yinghui 4; Jin, Shiyu 1; Yang, Ke 3; Qi, Xun 1
刊名	BIOACTIVE MATERIALS
	2021-04-01
卷号	6 期号:4 页码:916-927
关键词	Copper Biomaterials Angiogenesis Osteogenesis Antibacterial
DOI	10.1016/j.bioactmat.2020.09.017
通讯作者	Yang, Ke(kyang@imr.ac.cn) ; Qi, Xun(qixun716@hotmail.com)
英文摘要	Copper is an indispensable trace metal element in the human body, which is mainly absorbed in the stomach and small intestine and excreted into the bile. Copper is an important component and catalytic agent of many enzymes and proteins in the body, so it can influence human health through multiple mechanisms. Based on the biological functions and benefits of copper, an increasing number of researchers in the field of biomaterials have focused on developing novel copper-containing biomaterials, which exhibit unique properties in protecting the cardiovascular system, promoting bone fracture healing, and exerting antibacterial effects. Copper can also be used in promoting incisional wounds healing, killing cancer cells, Positron Emission Tomography (PET) imaging, radioimmunological tracing and radiotherapy of cancer. In the present review, the biological functions of copper in the human body are presented, along with an overview of recent progress in our understanding of the biological applications and development of copper-containing materials. Furthermore, this review also provides the prospective on the challenges of those novel biomaterials for future clinical applications.
资助项目	National Natural Science Foundation of China[81873918] ; National Natural Science Foundation of China[51631009] ; Construction Project of Liaoning Medical Imaging and Interventional Medical Engineering Research Center[18-006-9-01] ; Key Research and Serving Local Area Projects of the Educational Department of Liaoning Province, China[ZF2019005]
WOS研究方向	Engineering ; Materials Science
语种	英语
出版者	KEAI PUBLISHING LTD
WOS记录号	WOS:000616630300002
资助机构	National Natural Science Foundation of China ; Construction Project of Liaoning Medical Imaging and Interventional Medical Engineering Research Center ; Key Research and Serving Local Area Projects of the Educational Department of Liaoning Province, China
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/160675]
专题	金属研究所_中国科学院金属研究所
通讯作者	Yang, Ke; Qi, Xun
作者单位	1.China Med Univ, Dept Radiol, Key Lab Diagnost Imaging & Intervent Radiol Liaon, Affiliated Hosp 1, Shenyang 110001, Liaoning, Peoples R China 2.China Med Univ, Clin Res Ctr Malignant Tumor Liaoning Prov, Canc Hosp, Liaoning Canc Hosp & Inst, Shenyang 110042, Liaoning, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 4.Suzhou Silvan Med Co Ltd, Suzhou 215006, Peoples R China
推荐引用方式 GB/T 7714	Wang, Peng,Yuan, Yonghui,Xu, Ke,et al. Biological applications of copper-containing materials[J]. BIOACTIVE MATERIALS,2021,6(4):916-927.
APA	Wang, Peng.,Yuan, Yonghui.,Xu, Ke.,Zhong, Hongshan.,Yang, Yinghui.,...&Qi, Xun.(2021).Biological applications of copper-containing materials.BIOACTIVE MATERIALS,6(4),916-927.
MLA	Wang, Peng,et al."Biological applications of copper-containing materials".BIOACTIVE MATERIALS 6.4(2021):916-927.