Complexation of Fe(III)/Catechols in atmospheric aqueous phase and the consequent cytotoxicity assessment in human bronchial epithelial cells (BEAS-2B)

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Complexation of Fe(III)/Catechols in atmospheric aqueous phase and the consequent cytotoxicity assessment in human bronchial epithelial cells (BEAS-2B)
	Zhu, Zhonghong; Zhang, Jin; Lv, Guochun; George, Christian; Herrmann, Hartmut; Fu, Hongbo; Li, Dan; Zhang, Liwu; Sun, Xiaomin; Sun, Hao
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2020-10-01
卷号	202 页码:1-10
关键词	4-Nitrocatechol 4-Methylcatechol Aerosol Fe/catechols complex Oligomer Cytotoxicity
ISSN号	0147-6513
英文摘要	Recent research has shown that the complexation of metals-organics plays an important role in atmospheric particulate matter, whose health effects should be taken into account. This work investigates the interactions between catechols (CAs), i.e., 4-nitrocatechol (4NC) and 4-methylcatechol (4MC), and transition metals (i.e., Fe) in the aqueous phase dark reaction. The formation of Fe/CAs complexes and secondary organics products are analyzed by UV-Vis spectroscopy, stopped -flow spectroscopy, high-resolution mass spectrometry and Raman spectroscopy, while the insoluble particulate matter formed from the CAs/Fe mixtures are characterized by the FTIR, X-ray photoelectron spectroscopy (XPS) and thermogravimetric-quadrupole-mass spectrometry (TG-Q MS). On the basis of the density functional theory (DFT) calculation and experimental results, the possible formation pathways for the complexes of Fe(III) with 4NC (a proxy for organics) are proposed. The Fe/CAs complexes and organics products perhaps have significant sources of light absorption which play an important role in influencing the intensity of atmospheric radiation and particulate phase photochemistry. Besides, the cytotoxicity is tested as a function of concentrations for CAs/Fe mixtures in BEAS-2B cells. Our results show that CAs/Fe mixtures have strong association with cytotoxicity, indicating the mixtures have potential influence to human health.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/44639]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Zhu, Zhonghong,Zhang, Jin,Lv, Guochun,et al. Complexation of Fe(III)/Catechols in atmospheric aqueous phase and the consequent cytotoxicity assessment in human bronchial epithelial cells (BEAS-2B)[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2020,202:1-10.
APA	Zhu, Zhonghong.,Zhang, Jin.,Lv, Guochun.,George, Christian.,Herrmann, Hartmut.,...&Jiang, Guibin.(2020).Complexation of Fe(III)/Catechols in atmospheric aqueous phase and the consequent cytotoxicity assessment in human bronchial epithelial cells (BEAS-2B).ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,202,1-10.
MLA	Zhu, Zhonghong,et al."Complexation of Fe(III)/Catechols in atmospheric aqueous phase and the consequent cytotoxicity assessment in human bronchial epithelial cells (BEAS-2B)".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 202(2020):1-10.