Chitosan oligosaccharide and salicylic acid up-regulate gene expression differently in relation to the biosynthesis of artemisinin in Artemisia annua L.

	Chitosan oligosaccharide and salicylic acid up-regulate gene expression differently in relation to the biosynthesis of artemisinin in Artemisia annua L.
	Yin, Heng 1,2; Kjaer, Anders 1; Frette, Xavier C.3; Du, Yuguang 2; Christensen, Lars P.3; Jensen, Martin 1; Grevsen, Kai 1
刊名	process biochemistry
	2012-11-01
卷号	47 期号:11 页码:1559-1562
关键词	Artemisia annua L. Artemisinin Chitosan oligosaccharide Elicitor Gene expression Salicylic acid
通讯作者	尹恒 ; kaigrevsen
产权排序	2,1
英文摘要	artemisia annua l. is a traditional chinese medicinal plant used for treating fevers and malaria. the primary anti-malarial component is the sesquiterpene lactone peroxide artemisinin, which is accumulated in glandular trichomes. this study investigated the effect of treating plants with chitosan oligosaccharide (cos) and salicylic acid (sa) on both artemisinin production and gene expression related to the biosynthetic pathway of artemisinin. cos up-regulated the transcriptional levels of the genes ads and ttg1 2.5 fold and 1.8 fold after 48 h individually, whereas sa only up-regulated ads 2.0 fold after 48 h. lc-ms analysis showed that cos treatment increased artemisinin production in leaves slightly. these results suggest different responses of artemisia annua to cos and sa treatment. the limited effects of cos and sa on artemisinin production reveal that elicitors may not be a universal method for increasing artemisinin yield or the up-regulation takes longer than 48 h to be effective. (c) 2011 elsevier ltd. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; life sciences & biomedicine ; technology
类目[WOS]	biochemistry & molecular biology ; biotechnology & applied microbiology ; engineering, chemical
研究领域[WOS]	biochemistry & molecular biology ; biotechnology & applied microbiology ; engineering
关键词[WOS]	cultures ; yield
收录类别	SCI
语种	英语
WOS记录号	WOS:000313935400007
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/118006]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Aarhus Univ, Fac Sci & Technol, Dept Food Sci, DK-5792 Aarslev, Denmark 2.Chinese Acad Sci, Dalian Inst Chem Phys, Liaoning Prov Key Lab Carbohydrates, Dalian 116023, Peoples R China 3.Univ So Denmark, Inst Chem Engn Biotechnol & Environm Technol, Fac Engn, DK-5230 Odense, Denmark
推荐引用方式 GB/T 7714	Yin, Heng,Kjaer, Anders,Frette, Xavier C.,et al. Chitosan oligosaccharide and salicylic acid up-regulate gene expression differently in relation to the biosynthesis of artemisinin in Artemisia annua L.[J]. process biochemistry,2012,47(11):1559-1562.
APA	Yin, Heng.,Kjaer, Anders.,Frette, Xavier C..,Du, Yuguang.,Christensen, Lars P..,...&Grevsen, Kai.(2012).Chitosan oligosaccharide and salicylic acid up-regulate gene expression differently in relation to the biosynthesis of artemisinin in Artemisia annua L..process biochemistry,47(11),1559-1562.
MLA	Yin, Heng,et al."Chitosan oligosaccharide and salicylic acid up-regulate gene expression differently in relation to the biosynthesis of artemisinin in Artemisia annua L.".process biochemistry 47.11(2012):1559-1562.