The Instant Spontaneous Neuronal Activity Modulation of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Primary Insomnia | |
Bin, Zhao1; Yanzhi, Bi2,4; Liang, Li1; Jinling, Zhang1; Yang, Hong3; Lei, Zhang3; Jiakai, He1; Jiliang, Fang3; Peijing, Rong1 | |
刊名 | Frontiers in neuroscience |
2020-03-13 | |
DOI | 10.3389/fnins.2020.00205 |
产权排序 | 2 |
文献子类 | 实证研究 |
英文摘要 | Primary insomnia (PI) is associated with increased spontaneous neuronal activity. Transcutaneous auricular vagus nerve stimulation (taVNS) modulates brain function, and it is an effective treatment for primary insomnia. However, whether taVNS alleviates insomnia through modulating spontaneous neuronal activity is not fully clarified. This study aims to investigate the instant effect of taVNS in modulating spontaneous neuronal activity in PI patients using resting-state functional magnetic resonance imaging (rs-fMRI). Twenty-two PI subjects underwent rs-fMRI scanning prior and immediately after 30 min treatment of taVNS controlled by twenty healthy adults. Amplitude of low frequency fluctuations (ALFF) analysis was employed to assess the difference in spontaneous neuronal activity between PI patients and healthy adults, as well as between pre-treatment and post-treatment of taVNS. The taVNS-induced altered ALFF brain areas were then selected as regions of interest to perform the resting state functional connectivity (RSFC) analysis in PI patients. The right precuneus showed significantly increased ALFF in PI patients. After immediate taVNS treatment, the ALFF was significantly decreased in the right precuneus and increased in the left middle occipital gyrus. The RSFC in right precuneus with right angular, right superior frontal gyrus, and right middle frontal gyrus was significantly decreased. This study provides insights into the instant brain effects of taVNS on PI patients. |
URL标识 | 查看原文 |
收录类别 | SCI |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/40702] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Jiliang, Fang; Peijing, Rong |
作者单位 | 1.Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China 2.Department of Psychology, University of Chinese Academy of Sciences, Beijing, China 3.Department of Radiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China 4.CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China |
推荐引用方式 GB/T 7714 | Bin, Zhao,Yanzhi, Bi,Liang, Li,et al. The Instant Spontaneous Neuronal Activity Modulation of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Primary Insomnia[J]. Frontiers in neuroscience,2020. |
APA | Bin, Zhao.,Yanzhi, Bi.,Liang, Li.,Jinling, Zhang.,Yang, Hong.,...&Peijing, Rong.(2020).The Instant Spontaneous Neuronal Activity Modulation of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Primary Insomnia.Frontiers in neuroscience. |
MLA | Bin, Zhao,et al."The Instant Spontaneous Neuronal Activity Modulation of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Primary Insomnia".Frontiers in neuroscience (2020). |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论