DNAzyme based visual detection of DNA methylation

doi:10.1039/c7cc08427g

CORC > 成都生物研究所 > 中国科学院成都生物研究所 > 国家天然药物工程技术研究中心 > 天然产物研究

	DNAzyme based visual detection of DNA methylation
	Li, Mei 2; Zhang, Lei 1; Chen, Gangyi 2; Zhou, Jing 1; Yuan, Yi 2; Zou, Jiawei 2; Yuan, Mingming 1; Chen, Rong 2; Du, Feng 2; Cui, Xin 2
刊名	CHEMICAL COMMUNICATIONS
	2018
卷号	54 期号:14 页码:1710-1713
ISSN号	1359-7345
DOI	10.1039/c7cc08427g
产权排序	1
文献子类	Article
英文摘要	A novel colorimetric method which utilizes DNAzyme as a signal reporter was developed for DNA methylation detection. As low as 1/10(6) of methylated DNA could be successfully detected from unmethylated DNA. The discrimination ability is at least two orders of magnitude better than that of the methylation specific PCR.
学科主题	Chemistry
URL标识	查看原文
WOS关键词	HEPATITIS ; CANCER ; PCR
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000425105800008
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/30856]
专题	国家天然药物工程技术研究中心_天然产物研究
作者单位	1.Sichuan Acad Chinese Med Sci, Chengdu, Sichuan, Peoples R China 2.Univ Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China;
推荐引用方式 GB/T 7714	Li, Mei,Zhang, Lei,Chen, Gangyi,et al. DNAzyme based visual detection of DNA methylation[J]. CHEMICAL COMMUNICATIONS,2018,54(14):1710-1713.
APA	Li, Mei.,Zhang, Lei.,Chen, Gangyi.,Zhou, Jing.,Yuan, Yi.,...&Tang, Zhuo.(2018).DNAzyme based visual detection of DNA methylation.CHEMICAL COMMUNICATIONS,54(14),1710-1713.
MLA	Li, Mei,et al."DNAzyme based visual detection of DNA methylation".CHEMICAL COMMUNICATIONS 54.14(2018):1710-1713.