Evaluation of tofu as a potential tissue engineering scaffold
Huang, Jun3; Huang, Keqin3; You, Xinru3; Liu, Guiting3; Hollett, Geoffrey1; Kang, Yang2,3; Gu, Zhipeng3; Wu, Jun3
刊名JOURNAL OF MATERIALS CHEMISTRY B
2018
卷号6期号:9页码:1328-1334
ISSN号2050-750X
DOI10.1039/c7tb02852k
产权排序3
文献子类Article
英文摘要Tofu not only is a delicious vegetarian food, but also shows potential biomedical applications for its high protein content and typical porous scaffold structure. Herein, two kinds of porous soybean scaffolds were developed, the first based on the traditional tofu manufacturing processes, the second modified via covalent crosslinking. The morphology, physicochemical properties and biocompatibility in vitro and in vivo were systematically investigated. A similar porous micromorphology was observed in both the tofu scaffolds and crosslinked soybean protein scaffolds. Both scaffolds exhibited good cell proliferation and cellular adherence. No obvious inflammatory response was observed after subcutaneous implantation tests for either material. These results demonstrated that the tofu scaffolds or soybean protein scaffolds fabricated by tofu processing have potential as new food-source biomaterials in tissue engineering applications.
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WOS关键词SOY-PROTEIN FILMS ; BIOMATERIALS ; REGENERATION ; HYDROGEL ; PLATFORM
WOS研究方向Materials Science
语种英语
出版者ROYAL SOC CHEMISTRY
WOS记录号WOS:000426706900004
内容类型期刊论文
源URL[http://210.75.237.14/handle/351003/30849]  
专题生物多样性与生态系统服务领域_中国科学院山地生态恢复与生物资源利用重点实验室
作者单位1.Univ Calif San Diego, Mat Sci & Engn Program, La Jolla, CA 92093 USA;
2.Chinese Acad Sci, Chengdu Inst Biol, Key Lab Mt Ecol Restorat & Bioresource Utilizat, Chengdu 610041, Sichuan, Peoples R China
3.Sun Yat Sen Univ, Sch Engn, Key Lab Sensing Technol & Biomed Instrument Guang, Guangzhou 510006, Guangdong, Peoples R China;
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Huang, Jun,Huang, Keqin,You, Xinru,et al. Evaluation of tofu as a potential tissue engineering scaffold[J]. JOURNAL OF MATERIALS CHEMISTRY B,2018,6(9):1328-1334.
APA Huang, Jun.,Huang, Keqin.,You, Xinru.,Liu, Guiting.,Hollett, Geoffrey.,...&Wu, Jun.(2018).Evaluation of tofu as a potential tissue engineering scaffold.JOURNAL OF MATERIALS CHEMISTRY B,6(9),1328-1334.
MLA Huang, Jun,et al."Evaluation of tofu as a potential tissue engineering scaffold".JOURNAL OF MATERIALS CHEMISTRY B 6.9(2018):1328-1334.
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