Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate

doi:10.1016/j.ijbiomac.2021.06.148

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate
	Wei, Lijie 1,2,3; Sui, Haishan 1; Zhang, Jingjing 2,3; Guo, Zhanyong 2,3,4
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2021-09-01
卷号	186 页码:47-53
关键词	Inulin derivative Antioxidant activity CuAAC Click chemistry
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2021.06.148
通讯作者	Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要	In this paper, the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate was successfully synthesized by CuAAC Click chemistry. Detailed structural characterization was determined using FTIR spectroscopy, H-1 NMR spectroscopy, C-13 NMR spectroscopy, and elemental analysis. The antioxidant activities against hydroxyl radicals, superoxide radicals, and DPPH radicals were estimated in vitro respectively. The results showed that the antioxidant activity of the inulin derivative (3) was significantly enhanced compared with inulin. The inulin derivative (3) exhibited stronger radical scavenging abilities, especially against hydroxyl radicals and superoxide radicals. The scavenging values of the inulin derivative (3) were 98.2% and 95.4% at 1.6 mg/mL against hydroxyl radicals and superoxide radicals respectively. Besides, the scavenging value of the inulin derivative (3) increased by about 40% to scavenge DPPH radicals at 1.6 mg/mL than inulin. The results showed that the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate exhibited tremendously enhanced antioxidant activity compared with inulin. The synthetic strategy might provide an effective way to prepare novel inulin antioxidant biomaterials.
资助项目	Youth Innovation Promotion Association CAS[2020219] ; Natural Science Foundation of Shandong Province of China[ZR2019BD064] ; National Key Research and Development Pro-gram of China[2019YFD0900705] ; Natural Science Foundation of Shandong Province Science and Technology Development Plan[2019GHY112010]
WOS关键词	REACTIVE OXYGEN ; CHITOSAN DERIVATIVES ; ANTIFUNGAL ACTIVITY ; SCAVENGING ACTIVITY ; CLICK CHEMISTRY ; PHOSPHORYLATION ; COPOLYMERS ; NITROGEN ; STRESS
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
语种	英语
WOS记录号	WOS:000688432800006
资助机构	Youth Innovation Promotion Association CAS ; Natural Science Foundation of Shandong Province of China ; National Key Research and Development Pro-gram of China ; Natural Science Foundation of Shandong Province Science and Technology Development Plan
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/29703]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
通讯作者	Guo, Zhanyong
作者单位	1.Weifang Adm Market Regulat, Weifang Inspect & Testing Ctr, Weifang 261000, Shandong, Peoples R China 2.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Wei, Lijie,Sui, Haishan,Zhang, Jingjing,et al. Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,186:47-53.
APA	Wei, Lijie,Sui, Haishan,Zhang, Jingjing,&Guo, Zhanyong.(2021).Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,186,47-53.
MLA	Wei, Lijie,et al."Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 186(2021):47-53.