A comprehensive review on genetically modified fish: key techniques, applications and future prospects

doi:10.1111/raq.12538

	A comprehensive review on genetically modified fish: key techniques, applications and future prospects
	Wang, Yan 2,3; Hamid, Naima 2,3; Jia, Pan-Pan 1,2; Pei, De-Sheng 1,2,3
刊名	REVIEWS IN AQUACULTURE
	2021-02-18
页码	26
关键词	CRISPR Cas9 fluorescent fish gene editing genetically modified organisms (GMO) transgenic fish
ISSN号	1753-5123
DOI	10.1111/raq.12538
通讯作者	Pei, De-Sheng(peids@cigit.ac.cn)
英文摘要	Genetically modified fish is a general term used for whole fish whose DNA has been artificially altered by directly integrating (or deleting) single or multiple genes to introduce or modify a targeted character. Different techniques have been performed to produce genetically modified fish. Importantly, the introduction of various types of fluorescent proteins has dramatically expanded the range of applications of genetically modified fish. Currently, genetically modified fish have been widely employed as experimental models for medical science, pharmacology and environmental toxicology. The commercial application of genetically modified fish in aquaculture is still up for debate, although the first commercialization of genetically modified fish, GloFish, was in 2003, and further, the United States and Canada approved the commercial production and sale of the AquAdvantage Salmon. In this review, we discuss the principles and developmental history of fish transgenesis via gene transfer and gene-editing techniques, and their applications in diverse fields. Further, challenges and prospects associated with the genetically modified fish are discussed.
资助项目	CAS Team Project of the Belt and Road ; Chongqing Key Program of Basic Research and Advanced Exploration Project[cstc2019jcyj-zdxmX0035] ; Three Hundred Leading Talents in Scientific and Technological Innovation Program of Chongqing[CSTCCXLJRC201714] ; Program of China-Sri Lanka Joint Center for Water Technology Research and Demonstration by Chinese Academy of Sciences (CAS)/China-Sri Lanka Joint Center for Education and Research by CAS ; CAS[121311kysb20190071] ; CAS-TWAS[2017A8018537001]
WOS研究方向	Fisheries
语种	英语
出版者	WILEY
WOS记录号	WOS:000619192500001
内容类型	期刊论文
源URL	[http://119.78.100.138/handle/2HOD01W0/12937]
专题	中国科学院重庆绿色智能技术研究院
通讯作者	Pei, De-Sheng
作者单位	1.Henan Normal Univ, Coll Life Sci, Xinxiang, Henan, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Key Lab Reservoir Aquat Environm, Chongqing 400714, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yan,Hamid, Naima,Jia, Pan-Pan,et al. A comprehensive review on genetically modified fish: key techniques, applications and future prospects[J]. REVIEWS IN AQUACULTURE,2021:26.
APA	Wang, Yan,Hamid, Naima,Jia, Pan-Pan,&Pei, De-Sheng.(2021).A comprehensive review on genetically modified fish: key techniques, applications and future prospects.REVIEWS IN AQUACULTURE,26.
MLA	Wang, Yan,et al."A comprehensive review on genetically modified fish: key techniques, applications and future prospects".REVIEWS IN AQUACULTURE (2021):26.