Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

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	Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury
	Huang Wei 1,2; Cao Liang 1; Ye Zhenjiang 3; Lin Longshan 4; Chen Quanzhen 2; Dou Shuozeng 1
刊名	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
	2012-07-01
卷号	30 期号:4 页码:569-579
关键词	mercury (Hg) antioxidants lipid peroxidation bioaccumulation of metal
ISSN号	0254-4059
通讯作者	Dou, SZ (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China.
英文摘要	To understand mercury (Hg) toxicity in marine fish, we measured Hg accumulation in juvenile Japanese flounder (Paralichthys olivaceus) and assessed the effects on growth and antioxidant responses. After Hg exposure (control, 5, 40, and 160 mu g/L Hg) for 28 d, fish growth was significantly reduced. The accumulation of Hg in fish was dose-dependent and tissue-specific, with the maximum accumulation in kidney and liver, followed by gills, bone, and muscle. Different antioxidants responded differently to Hg exposure to cope with the induction of lipid peroxidation (LPO), which was also tissue-specific and dosedependent. As Hg concentration increased, superoxide dismutase (SOD) and catalase (CAT) activities increased significantly, whereas glutathione S -transferase (GST) activity and glutathione (GSH) levels decreased significantly in the gills. SOD and glutathione peroxidase (GPx) activities and the GSH level increased significantly in the liver. SOD activity and GSH levels increased significantly, but CAT activity decreased significantly with an increase in Hg concentration in the kidney. LPO was induced significantly by elevated Hg in the gills and kidney but was least affected in the liver. Therefore, oxidative stress biomarkers in gills were more sensitive than those in the liver and kidney to Hg exposure. Thus, the gills have potential as bioindicators for evaluating Hg toxicity in juvenile flounder.
学科主题	Limnology ; Oceanography
收录类别	SCI
原文出处	10.1007/s00343-012-1210-z
语种	英语
WOS记录号	WOS:000305906700008
公开日期	2013-09-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/12451]
专题	海洋研究所_海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.State Ocean Adm, Inst Oceanog 2, Lab Marine Ecosyst & Biogeochem, Hangzhou 310012, Zhejiang, Peoples R China 3.Ocean Univ China, Fishery Coll, Qingdao 266003, Peoples R China 4.State Ocean Adm, Inst Oceanog 2, Xiamen 361005, Peoples R China
推荐引用方式 GB/T 7714	Huang Wei,Cao Liang,Ye Zhenjiang,et al. Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2012,30(4):569-579.
APA	Huang Wei,Cao Liang,Ye Zhenjiang,Lin Longshan,Chen Quanzhen,&Dou Shuozeng.(2012).Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,30(4),569-579.
MLA	Huang Wei,et al."Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 30.4(2012):569-579.