SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters

	SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters
	Wang Li; Shen Chun; Xu Minghua
刊名	Science China. Chemistry
	2011
卷号	54 期号:1 页码:61
关键词	β-amino acid ester samarium diiodide N-tert-butanesulfinyl imine Reformatsky reaction β-lactam 3-aminoindan-1one asymmetric synthesis
ISSN号	1674-7291
英文摘要	A facile and efficient method for the stereoselective synthesis of β-amino acid esters via SmI2-promoted imino-Reformatsky reaction is described. Asymmetric addition of tert-butyl bromoacetate to N-tert-butanesulfinyl aldimines afforded β-amino acid esters in moderate to high yields with excellent diastereoselectivities. The synthetic utilities of the tert-butyl β-amino acid esters were expanded by the preparation of β-lactams and 3-aminoindan-1-ones derivatives
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/293172]
专题	中国科学院上海药物研究所
作者单位	中国科学院上海药物研究所
推荐引用方式 GB/T 7714	Wang Li,Shen Chun,Xu Minghua. SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters[J]. Science China. Chemistry,2011,54(1):61.
APA	Wang Li,Shen Chun,&Xu Minghua.(2011).SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters.Science China. Chemistry,54(1),61.
MLA	Wang Li,et al."SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters".Science China. Chemistry 54.1(2011):61.