SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters | |
Wang Li; Shen Chun; Xu Minghua | |
刊名 | Science China. Chemistry
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2011 | |
卷号 | 54期号:1页码:61 |
关键词 | β-amino acid ester samarium diiodide N-tert-butanesulfinyl imine Reformatsky reaction β-lactam 3-aminoindan-1one asymmetric synthesis |
ISSN号 | 1674-7291 |
英文摘要 | A facile and efficient method for the stereoselective synthesis of β-amino acid esters via SmI2-promoted imino-Reformatsky reaction is described. Asymmetric addition of tert-butyl bromoacetate to N-tert-butanesulfinyl aldimines afforded β-amino acid esters in moderate to high yields with excellent diastereoselectivities. The synthetic utilities of the tert-butyl β-amino acid esters were expanded by the preparation of β-lactams and 3-aminoindan-1-ones derivatives |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/293172] ![]() |
专题 | 中国科学院上海药物研究所 |
作者单位 | 中国科学院上海药物研究所 |
推荐引用方式 GB/T 7714 | Wang Li,Shen Chun,Xu Minghua. SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters[J]. Science China. Chemistry,2011,54(1):61. |
APA | Wang Li,Shen Chun,&Xu Minghua.(2011).SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters.Science China. Chemistry,54(1),61. |
MLA | Wang Li,et al."SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters".Science China. Chemistry 54.1(2011):61. |
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