Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava

doi:10.1016/j.fitote.2019.03.018

	Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava
	Wu, Qihao 2,3,4; Li, Heng 1,2; Yang, Min 1,2; Jia, Ai-Qun 5; Tang, Wei 2; Wang, Hong 3,4; Guo, Yue-Wei 2,3,4
刊名	FITOTERAPIA
	2019-04-01
卷号	134 页码:481-484
关键词	Soft coral Cembranoid Lemnalia flava
ISSN号	0367-326X
DOI	10.1016/j.fitote.2019.03.018
通讯作者	Wang, Hong() ; Guo, Yue-Wei(ywguo@simm.ac.cn)
英文摘要	Further chemical investigation of the South China Sea soft coral Lemnalia flava resulted in the isolation and characterization of two new cembranoids, namely, xishaflavalins G and H (1 and 2), along with three known related compounds (3-5). The structures of the new compounds were elucidated by detailed spectroscopic analysis and by the comparison of their spectroscopic data with those reported in the literature. The discovery of cembrane-type diterpenes from soft coral of the genus Lemnalia was reported for the first time. In addition, compound 5 exhibited moderate. inhibitory effects on the ConA-induced T lymphocytes and/or lipopolysaccharide (LPS)-induced B lymphocytes proliferation.
资助项目	National Key Research and Development Program of China[2018YFC0310903] ; Drug Innovation Major Project[2018ZX09711-001-001-009] ; National Natural Science Foundation of China (NSFC)[81520108028] ; National Natural Science Foundation of China (NSFC)[21672230] ; National Natural Science Foundation of China (NSFC)[81773628] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403]
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000468710300061
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/289818]
专题	中国科学院上海药物研究所
通讯作者	Wang, Hong; Guo, Yue-Wei
作者单位	1.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China 3.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China 4.Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Zhejiang, Peoples R China 5.Hainan Univ, Minist Educ, Key Lab Trop Biol Resources, State Key Lab Marine Resource Utilizat South Chin, Haikou 570228, Hainan, Peoples R China
推荐引用方式 GB/T 7714	Wu, Qihao,Li, Heng,Yang, Min,et al. Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava[J]. FITOTERAPIA,2019,134:481-484.
APA	Wu, Qihao.,Li, Heng.,Yang, Min.,Jia, Ai-Qun.,Tang, Wei.,...&Guo, Yue-Wei.(2019).Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava.FITOTERAPIA,134,481-484.
MLA	Wu, Qihao,et al."Two new cembrane-type diterpenoids from the xisha soft coral Lemnalia flava".FITOTERAPIA 134(2019):481-484.