Silver-mediated synthesis of novel 3-CF3/CN/phosphonate-substituted pyrazoles as pyrrolomycin analogues from 3-formylchromones and diazo compounds | |
Peng, Xiaofeng1,2; Zhang, Xiaofei1; Li, Shunyao1,2; Lu, Yunfu1,2; Lan, Lefu1,2; Yang, Chunhao1,2 | |
刊名 | ORGANIC CHEMISTRY FRONTIERS |
2019-06-07 | |
卷号 | 6期号:11页码:1775-1779 |
ISSN号 | 2052-4129 |
DOI | 10.1039/c9qo00324j |
通讯作者 | Lan, Lefu(llan@simm.ac.cn) ; Yang, Chunhao(chyang@simm.ac.cn) |
英文摘要 | Herein, a simple and regioselective synthesis of (2-hydroxyphenyl)(3-(trifluoromethyl/ cyano/ phosphonate)- 1H-pyrazol-5-yl) methanones as pyrrolomycin analogues was reported. This reaction could proceed from 3-formylchromones and the corresponding diazo compounds by a silver-mediated one-pot cascade reaction under mild conditions with a broad substrate scope. Most of all, some products displayed potent antibacterial activities. |
资助项目 | Science and Technology Commission of Shanghai Municipality[18431907100] ; Shanghai Sailing Program[17YF1423400] |
WOS关键词 | REGIOSELECTIVE SYNTHESIS ; BIOLOGICAL EVALUATION ; INSECTICIDAL CHLORFENAPYR ; DESIGN ; CYCLOADDITION ; FLUORINE ; FLOW |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000469257000004 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/289638] |
专题 | 中国科学院上海药物研究所 |
通讯作者 | Lan, Lefu; Yang, Chunhao |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Sch Pharm, 19A Yuquan Rd, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Peng, Xiaofeng,Zhang, Xiaofei,Li, Shunyao,et al. Silver-mediated synthesis of novel 3-CF3/CN/phosphonate-substituted pyrazoles as pyrrolomycin analogues from 3-formylchromones and diazo compounds[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(11):1775-1779. |
APA | Peng, Xiaofeng,Zhang, Xiaofei,Li, Shunyao,Lu, Yunfu,Lan, Lefu,&Yang, Chunhao.(2019).Silver-mediated synthesis of novel 3-CF3/CN/phosphonate-substituted pyrazoles as pyrrolomycin analogues from 3-formylchromones and diazo compounds.ORGANIC CHEMISTRY FRONTIERS,6(11),1775-1779. |
MLA | Peng, Xiaofeng,et al."Silver-mediated synthesis of novel 3-CF3/CN/phosphonate-substituted pyrazoles as pyrrolomycin analogues from 3-formylchromones and diazo compounds".ORGANIC CHEMISTRY FRONTIERS 6.11(2019):1775-1779. |
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