One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones

doi:10.3390/molecules24163017

	One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones
	Yuan, Jiaqi 1,2; He, Qian 1; Song, Shanshan 1; Zhang, Xiaofei 1; Miao, Zehong 1; Yang, Chunhao 1,2
刊名	MOLECULES
	2019-08-01
卷号	24 期号:16 页码:12
关键词	3-(2-hydroxybenzoyl)-1-aza-anthraquinones chromones anti-proliferation agent
DOI	10.3390/molecules24163017
通讯作者	Zhang, Xiaofei(xiaofeizhang@simm.ac.cn) ; Yang, Chunhao(chyang@simm.ac.cn)
英文摘要	Herein, a direct strategy to synthesize 3-(2-hydroxybenzoyl)-1-aza-anthraquinones with excellent efficiency, mild conditions, and benign functional group compatibility was reported. A variety of 3-formylchromone compounds were employed as compatible substrates and this protocol gave the 3-(2-hydroxybenzoyl)-1-aza-anthraquinone derivatives in good to excellent yields without inert gas and expensive transition metal catalysts. Some compounds displayed good anti-proliferative activities.
资助项目	Science and Technology Commission of Shanghai Municipality[18431907100] ; Shanghai Sailing Program[17YF1423400] ; SKLDR/SIMM[SIMM1903ZZ-03]
WOS关键词	CATALYZED INTRAMOLECULAR CYCLIZATION ; DIELS-ALDER ; FACILE ROUTE ; ANALOGS ; 3-FORMYLCHROMONES ; CYCLOADDITION ; KALASINAMIDE ; DERIVATIVES
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MDPI
WOS记录号	WOS:000482998900038
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/288680]
专题	中国科学院上海药物研究所
通讯作者	Zhang, Xiaofei; Yang, Chunhao
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Sch Pharm, 19A Yuquan Rd, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Yuan, Jiaqi,He, Qian,Song, Shanshan,et al. One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones[J]. MOLECULES,2019,24(16):12.
APA	Yuan, Jiaqi,He, Qian,Song, Shanshan,Zhang, Xiaofei,Miao, Zehong,&Yang, Chunhao.(2019).One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones.MOLECULES,24(16),12.
MLA	Yuan, Jiaqi,et al."One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones".MOLECULES 24.16(2019):12.