A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection

doi:10.1016/j.jmst.2020.04.070

CORC > 金属研究所 > 中国科学院金属研究所

	A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection
	Hao, Yabin 1,2; Fang, Minghe 1,2; Xu, Chuan 1; Ying, Zhe 1; Wang, Han 1,2; Zhang, Rui 3; Cheng, Hui-Ming 1,2,4; Zeng, You 1,2
刊名	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
	2021-03-10
卷号	66 页码:57-63
关键词	Graphene Laminated structure Electrode Glucose detection Biosensor
ISSN号	1005-0302
DOI	10.1016/j.jmst.2020.04.070
通讯作者	Zhang, Rui(zzzrrr1234@sina.com) ; Cheng, Hui-Ming(cheng@imr.ac.cn) ; Zeng, You(yzeng@imr.ac.cn)
英文摘要	Graphene oxide (GO) has received considerable attention for glucose detection because of high surface area, abundant functional groups, and good biocompatibility. Defects and functional groups of the GO are beneficial to immobilization of glucose oxidase (GOD), but sacrificing electron-transfer capability for highly-sensitive detection. In order to obtain high GOD loading and highly-sensitive detection of biosensors, we first designed and fabricated a graphene-laminated electrode by combining GO and edge-functionalized graphene (FG) layers together onto glassy-carbon electrode. The graphene-laminated electrodes exhibited faster electron transfer rate, higher GOD loading of 3.80 x 10(-)(9) mol.cm(-2), and higher detection sensitivity of 46.71 mu A.mM(-1).cm(-2) than other graphene-based biosensors reported in literature. Such high performance is mainly attributed to the abundant functional groups of GO, high electrical conductivity of FG, and strong interactions between components in the graphene-laminated electrodes. By virtue of their high enzyme loading and highly-sensitive detection, the graphene-laminated electrodes show great potential to be widely used as high-performance biosensors in the field of medical diagnosis. (C) 2021 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
资助项目	National Natural Science Foundation of China[51802317] ; Liaoning Natural Science Foundation[2019JH3/30100008] ; Liaoning Key Research & Development Project[2019JH2/10300045] ; Joint Fund for Advanced Equipment and Aerospace Science and Technology of China[6141B061306]
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
语种	英语
出版者	JOURNAL MATER SCI TECHNOL
WOS记录号	WOS:000610200200007
资助机构	National Natural Science Foundation of China ; Liaoning Natural Science Foundation ; Liaoning Key Research & Development Project ; Joint Fund for Advanced Equipment and Aerospace Science and Technology of China
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/159108]
专题	金属研究所_中国科学院金属研究所
通讯作者	Zhang, Rui; Cheng, Hui-Ming; Zeng, You
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Peoples R China 3.Liaoning Canc Hosp & Inst, Shenyang 110042, Peoples R China 4.Tsinghua Berkeley Shenzhen Inst, Shenzhen Geim Graphene Ctr, Shenzhen 518055, Peoples R China
推荐引用方式 GB/T 7714	Hao, Yabin,Fang, Minghe,Xu, Chuan,et al. A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2021,66:57-63.
APA	Hao, Yabin.,Fang, Minghe.,Xu, Chuan.,Ying, Zhe.,Wang, Han.,...&Zeng, You.(2021).A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,66,57-63.
MLA	Hao, Yabin,et al."A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 66(2021):57-63.