Serum pepsinogen and osteopontin for gastric cancer screening

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	Serum pepsinogen and osteopontin for gastric cancer screening
	Gong YueHua; Sun LiPing; Yuan Yuan
刊名	CHINESE JOURNAL OF CANCER RESEARCH
	2007
卷号	19 期号:3 页码:153-158
关键词	HELICOBACTER-PYLORI METASTASIS EXPRESSION PROSTATE PROTEIN ANTIBODIES JAPANESE MARKERS PLASMA BREAST gastric cancer cancer screening serology tumor marker
ISSN号	1000-9604
其他题名	Serum Pepsinogen and Osteopontin for Gastric Cancer Screening
英文摘要	Objective: To investigate the value of combined assay of serum pepsinogen (PG) and osteopontin (OPN) levels for gastric cancer screening. Methods: Fasting serum pepsinogen I, II and OPN concentration were measured by ELISA in 570 subjects. The cut off points for PG and OPN were determined using ROC. Results: Using serum PGI concentration = 34 ng/ml or >= 30.44 ng/ml (based on ROC) for gastric cancer screening had superior specificity, positive and negative predictive values compared with PG or OPN screening only. The sensitive and specificity of combining serum PG and OPN assay were both more than 70% compared with PG or OPN screening alone. Conclusion: Combining serum PG and OPN assay for gastric cancer screening is superior to PG or OPN level only. This may be a new method for gastric cancer mass screening.
语种	英语
CSCD记录号	CSCD:2927947
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/145725]
专题	金属研究所_中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Gong YueHua,Sun LiPing,Yuan Yuan. Serum pepsinogen and osteopontin for gastric cancer screening[J]. CHINESE JOURNAL OF CANCER RESEARCH,2007,19(3):153-158.
APA	Gong YueHua,Sun LiPing,&Yuan Yuan.(2007).Serum pepsinogen and osteopontin for gastric cancer screening.CHINESE JOURNAL OF CANCER RESEARCH,19(3),153-158.
MLA	Gong YueHua,et al."Serum pepsinogen and osteopontin for gastric cancer screening".CHINESE JOURNAL OF CANCER RESEARCH 19.3(2007):153-158.