Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material

doi:10.1016/j.msec.2019.05.003

CORC > 金属研究所 > 中国科学院金属研究所

	Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material
	Ma, Zheng 2; Gao, Ming 1,2; Na, Di 3; Li, Yangde 4; Tan, Lili 2; Yang, Ke 2
刊名	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
	2019-10-01
卷号	103 页码:8
关键词	Fe-Mn-C-Cu alloy Biodegradable Anti-infection Urinary implant material Anti-encrustation
ISSN号	0928-4931
DOI	10.1016/j.msec.2019.05.003
通讯作者	Tan, Lili(lltan@imr.ac.cn) ; Yang, Ke(kyang@imr.ac.cn)
英文摘要	Biodegradable Fe based alloys have been investigated for fracture fixation and cardiovascular support to overcome complications of permanent implants. This study was focused on the development of a new Fe-Mn-CCu alloy with antibacterial and anti-encrustation properties as a urinary implant material. The microstructure and mechanical properties of the alloy were studied. The degradation behavior, antibacterial and anti-encrustation properties were evaluated by immersion test, antibacterial test and encrustation test, respectively. The results showed that Fe-Mn-C-Cu alloy was a non-magnetic, biodegradable, anti-bacterial and anti-encrustation alloy that could inhibit the biofilm and stone formations on its surface through the dual effects of degradation and Cu ions release. The study revealed the preliminary mechanisms of anti-infection and anti-encrustation for Fe-Mn-C-Cu alloy due to the continuous release of Cu2+ ions, which provides a new idea for application of biodegradable Fe-based material and the treatment of urinary tract infections and stones in the urinary system.
资助项目	Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project[Z18-0-027]
WOS研究方向	Materials Science
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000480664900021
资助机构	Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/134995]
专题	金属研究所_中国科学院金属研究所
通讯作者	Tan, Lili; Yang, Ke
作者单位	1.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China 3.China Med Univ, Dept Surg Oncol, Affiliated Hosp 1, Beijing, Peoples R China 4.Dongguan Eontech Co Ltd, Dongguan 523662, Peoples R China
推荐引用方式 GB/T 7714	Ma, Zheng,Gao, Ming,Na, Di,et al. Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019,103:8.
APA	Ma, Zheng,Gao, Ming,Na, Di,Li, Yangde,Tan, Lili,&Yang, Ke.(2019).Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,103,8.
MLA	Ma, Zheng,et al."Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 103(2019):8.