Recent Advances on Biodegradable MgYREZr Magnesium Alloy

doi:10.11900/0412.1961.2017.00266

CORC > 金属研究所 > 中国科学院金属研究所

	Recent Advances on Biodegradable MgYREZr Magnesium Alloy
	Tan Lili 1; Chen Junxiu 1,2; Yu Xiaoming 1; Yang Ke 1
刊名	ACTA METALLURGICA SINICA
	2017-10-11
卷号	53 期号:10 页码:1207-1214
关键词	MgYREZr alloy microstructure mechanical property biodegradable property biocompatibility
ISSN号	0412-1961
DOI	10.11900/0412.1961.2017.00266
通讯作者	Tan Lili(lltan@imr.ac.cn)
英文摘要	In recent years, magnesium and its alloys as biodegradable materials have attracted much attention. Biodegradable MgYREZr, mainly WE43 alloy, with good integrated properties has been studied in favor. In this paper, the microstructure, mechanical properties, biodegradable property and biocompatibility of biodegradable MgYREZr alloy were reviewed, as well as the clinical results of the bone fixation screws developed in Germany using the alloy with similar composition to WE43. MgYREZr alloy presents uniform microstructure and higher mechanical properties after large plastic deformation with the grain size of less than 1 mm. The RE elements can be dissolved and stabilize the corrosion layer, which can decrease the degradation rate of the alloy accompanying with optimized heat treatment. The animal tests showed biocompatibility and good bioactivity. Clinical tests showed the MgYREZr alloy screws presented equivalent to titanium screws for the treatment of mild hallux valgus deformities, however resorption cysts was revealed by X-rays when the acute scaphoid fractures were treated with a double-threaded screw made of MgYREZr, and it was only after 6 months that the fractures were consolidated enough to allow physical work. So for different clinical cases, the degradation and biological behaviors of MgYREZr alloys need to be further studied in vitro and in vivo. To control the degradation rates to meet the different clinical requirements is still a major obstacle for biodegradable MgYREZr alloys to enlarge their clinical application.
资助项目	National Natural Science Foundation of China[81401773] ; National Natural Science Foundation of China[31500777]
WOS研究方向	Metallurgy & Metallurgical Engineering
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000416301400006
资助机构	National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/125447]
专题	金属研究所_中国科学院金属研究所
通讯作者	Tan Lili
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Tan Lili,Chen Junxiu,Yu Xiaoming,et al. Recent Advances on Biodegradable MgYREZr Magnesium Alloy[J]. ACTA METALLURGICA SINICA,2017,53(10):1207-1214.
APA	Tan Lili,Chen Junxiu,Yu Xiaoming,&Yang Ke.(2017).Recent Advances on Biodegradable MgYREZr Magnesium Alloy.ACTA METALLURGICA SINICA,53(10),1207-1214.
MLA	Tan Lili,et al."Recent Advances on Biodegradable MgYREZr Magnesium Alloy".ACTA METALLURGICA SINICA 53.10(2017):1207-1214.