Salinity as a predominant factor modulating the distribution patterns of antibiotic resistance genes in ocean and river beach soils

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 城市与区域生态国家重点实验室

	Salinity as a predominant factor modulating the distribution patterns of antibiotic resistance genes in ocean and river beach soils
	Zhang, Yu-Jing ; Hu, Hang-Wei ; Yan, Hui ; Wang, Jun-Tao ; Lam, Shu Kee ; Chen, Qing-Lin ; Chen, Deli ; He, Ji-Zheng
刊名	SCIENCE OF THE TOTAL ENVIRONMENT
	2019-06-10
卷号	668 页码:193-203
关键词	Soil resistome Soil salinity Beach soils Bacterial community Public health
ISSN号	0048-9697
英文摘要	Growing evidence points to the pivotal role of the environmental factors in influencing the transmission of antibiotic resistance genes (ARGs) and the propagation of resistant human pathogens. However, our understanding of the ecological and evolutionary environmental factors that contribute to development and dissemination of antibiotic resistance is lacking. Here, we profiled a wide variety of ARGs using the high-throughput quantitative PCR analysis in 61 soil samples collected from ocean and river beaches, which are hotspots for human activities and platforms for potential transmission of environmental ARGs to human pathogens. We identified the dominant abiotic and biotic factors influencing the diversity, abundance and composition of ARGs in these ecosystems. A total of 110 ARGs conferring resistance to eight major categories of antibiotics were detected. The core resistome was mainly affiliated into beta-lactam and multidrug resistance, accounting for 66.9% of the total abundance of ARGs. The oprj gene conferring resistance to multidrug was the most widespread ARG subtype detected in all the samples. The relative abundances of total ARGs and core resistome were significantly correlated with salinity-related properties including electrical conductivity and concentrations of sodium and chloride. Random forest analysis and structural equation modelling revealed that salinity was the most important factor modulating the distribution patterns of beach soil ARGs after accounting for multiple drivers. These findings suggest that beach soil is a rich reservoir of ARGs and that salinity is a predominant factor shaping the distribution patterns of soil resistome. (C) 2019 Elsevier B.V. All rights reserved.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/42787]
专题	生态环境研究中心_城市与区域生态国家重点实验室
作者单位	1.Hebei Agr Univ, Coll Anim Sci & Technol, Baoding 071000, Peoples R China 2.Univ Melbourne, Fac Vet & Agr Sci, Melbourne, Vic 3010, Australia 3.Chinese Acad Sci, State Key Lab Urban & Reg Ecol, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yu-Jing,Hu, Hang-Wei,Yan, Hui,et al. Salinity as a predominant factor modulating the distribution patterns of antibiotic resistance genes in ocean and river beach soils[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2019,668:193-203.
APA	Zhang, Yu-Jing.,Hu, Hang-Wei.,Yan, Hui.,Wang, Jun-Tao.,Lam, Shu Kee.,...&He, Ji-Zheng.(2019).Salinity as a predominant factor modulating the distribution patterns of antibiotic resistance genes in ocean and river beach soils.SCIENCE OF THE TOTAL ENVIRONMENT,668,193-203.
MLA	Zhang, Yu-Jing,et al."Salinity as a predominant factor modulating the distribution patterns of antibiotic resistance genes in ocean and river beach soils".SCIENCE OF THE TOTAL ENVIRONMENT 668(2019):193-203.