Deep learning -based multi -view fusion model for screening 2019 novel coronavirus pneumonia: A multicentre study
Wu, Xiangjun5,6; Hui, Hui4,6; Niu, Meng1; Li, Liang8; Wang, Li7; He, Bingxi4,6; Yang, Xin6; Li, Li3; Li, Hongjun3; Tian, Jie2,4,6
刊名EUROPEAN JOURNAL OF RADIOLOGY
2020-07-01
卷号128期号:109041页码:9
关键词Coronavirus disease 2019 Deep learning Multi-view model Computed tomography
ISSN号0720-048X
DOI10.1016/j.ejrad.2020.109041
英文摘要

Purpose: To develop a deep learning-based method to assist radiologists to fast and accurately identify patients with COVID-19 by CT images. Methods: We retrospectively collected chest CT images of 495 patients from three hospitals in China. 495 datasets were randomly divided into 395 cases (80%, 294 of COVID-19, 101 of other pneumonia) of the training set, 50 cases (10%, 37 of COVID-19, 13 of other pneumonia) of the validation set and 50 cases (10%, 37 of COVID-19, 13 of other pneumonia) of the testing set. We trained a multi-view fusion model using deep learning network to screen patientswithCOVID-19 using CTimageswiththe maximum lungregions inaxial,coronal and sagittal views. The performance of the proposed model was evaluated by both the validation and testing sets. Results: The multi-view deep learning fusion model achieved the area under the receiver-operating characteristics curve (AUC) of 0.732, accuracy of 0.700, sensitivity of 0.730 and specificity of 0.615 in validation set. In the testing set, we can achieve AUC, accuracy, sensitivity and specificity of 0.819, 0.760, 0.811 and 0.615 respectively. Conclusions: Based on deep learning method, the proposed diagnosis model trained on multi-view images of chest CT images showed great potential to improve the efficacy of diagnosis and mitigate the heavy workload of radiologists for the initial screening of COVID-19 pneumonia.

资助项目National Key Research and Development Program of China[2017YFA0700401] ; National Key Research and Development Program of China[2016YFC0103803] ; National Key Research and Development Program of China[2017YFA0205200] ; National Key Research and Development Program of China[2019YFC0118100] ; Novel Coronavirus Pneumonia Emergency Key Project of Science and Technology of Hubei Province[2020FCA015] ; National Natural Science Foundation of China[81671851] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81527805] ; National Natural Science Foundation of China[81871332] ; National Natural Science Foundation of China[81227901] ; Chinese Academy of Sciences[XDB32030200] ; Chinese Academy of Sciences[YJKYYQ20170075]
WOS研究方向Radiology, Nuclear Medicine & Medical Imaging
语种英语
出版者ELSEVIER IRELAND LTD
WOS记录号WOS:000540453900003
资助机构National Key Research and Development Program of China ; Novel Coronavirus Pneumonia Emergency Key Project of Science and Technology of Hubei Province ; National Natural Science Foundation of China ; Chinese Academy of Sciences
内容类型期刊论文
源URL[http://ir.ia.ac.cn/handle/173211/39840]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Niu, Meng; Tian, Jie; Zha, Yunfei
作者单位1.China Med Univ, Hosp 1, Intervent Radiol Dept, Shenyang 110001, Peoples R China
2.Beihang Univ, Sch Med, Beijing Adv Innovat Ctr Big Data Based Precis Med, Beijing 100083, Peoples R China
3.Capital Med Univ, Beijing Youan Hosp, Dept Radiol, Beijing 100069, Peoples R China
4.Univ Chinese Acad Sci, Beijing, Peoples R China
5.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 100190, Peoples R China
6.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
7.Wuhan Univ, Renmin Hosp, Dept Infect Prevent & Control Off, Wuhan 430060, Peoples R China
8.Wuhan Univ, Renmin Hosp, Dept Radiol, Wuhan 430060, Peoples R China
推荐引用方式
GB/T 7714
Wu, Xiangjun,Hui, Hui,Niu, Meng,et al. Deep learning -based multi -view fusion model for screening 2019 novel coronavirus pneumonia: A multicentre study[J]. EUROPEAN JOURNAL OF RADIOLOGY,2020,128(109041):9.
APA Wu, Xiangjun.,Hui, Hui.,Niu, Meng.,Li, Liang.,Wang, Li.,...&Zha, Yunfei.(2020).Deep learning -based multi -view fusion model for screening 2019 novel coronavirus pneumonia: A multicentre study.EUROPEAN JOURNAL OF RADIOLOGY,128(109041),9.
MLA Wu, Xiangjun,et al."Deep learning -based multi -view fusion model for screening 2019 novel coronavirus pneumonia: A multicentre study".EUROPEAN JOURNAL OF RADIOLOGY 128.109041(2020):9.
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