bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas

doi:10.1007/s00343-019-9070-4

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas
	Chen Na 2,3; Li Li 1; Li Chenghua 3; Lin Zhihua 2; Meng Jie 1; Liu Sheng 1; Song Kai 1; Bao Yongbo 2
刊名	JOURNAL OF OCEANOLOGY AND LIMNOLOGY
	2019-12-05
页码	7
关键词	Crassostrea gigas basic helix-loop-helix (bHLH) re-sequencing single nucleotide polymorphism (SNP) shot growth traits
ISSN号	2096-5508
DOI	10.1007/s00343-019-9070-4
英文摘要	The basic helix-loop-helix (bHLH) genes encode a large superfamily of transcription factors in the Pacific oyster (Crassostrea gigas), and play a very important role in regulation of growth and development. To investigate the oyster growth traits and the associations with bHLH genes variations, we analyzed the gene polymorphisms-traits association in a wild population, and confirmed the results in another independent wild population by targeted gene re-sequencing and SNPshot analysis. After screening the single nucleotide polymorphisms (SNPs) in three candidate genes of the bHLH family (88 bHLH genes in two wild oyster populations in total), we identified the allele CgLoblHLH4-T/G located in the exon of the CgLoblHLH4 gene. This allele is a non-synonymous mutation (Phe/Leu) with an extremely significant association with shell width (P<0.01) and allele G is beneficial to shell width. This SNP on the CgLoblHLH4 gene might have a potential value as a genetic marker of growth traits that could be used in breeding in C. gigas in the future.
资助项目	National Key R&D Program of China[2018YFD0901400] ; National Natural Science Foundation of China[31672678] ; Ningbo Municipal Science and Technology International Cooperation Research Projects[2016D10017] ; Zhejiang Provincial Major Program of Science and Technology[2016C02055-9]
WOS研究方向	Marine & Freshwater Biology ; Oceanography
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000500871700004
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.qdio.ac.cn/handle/337002/163852]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Bao Yongbo
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China 2.Zhejiang Wanli Univ, Coll Biol & Environm Sci, Zhejiang Key Lab Aquat Germplasm Resources, Ningbo 315121, Zhejiang, Peoples R China 3.Ningbo Univ, Sch Marine Sci, Ningbo 315211, Zhejiang, Peoples R China
推荐引用方式 GB/T 7714	Chen Na,Li Li,Li Chenghua,et al. bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2019:7.
APA	Chen Na.,Li Li.,Li Chenghua.,Lin Zhihua.,Meng Jie.,...&Bao Yongbo.(2019).bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,7.
MLA	Chen Na,et al."bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas".JOURNAL OF OCEANOLOGY AND LIMNOLOGY (2019):7.