Evaluating an intervention for neural tube defects in coal mining cites in China: a temporal and spatial analysis

doi:10.1093/inthealth/ihaa035

	Evaluating an intervention for neural tube defects in coal mining cites in China: a temporal and spatial analysis
	Zhang, Ningxu 2,3; Liao, Yilan 1,2; Ren, Zhoupeng 2
刊名	INTERNATIONAL HEALTH
	2021-03-01
卷号	13 期号:2 页码:161-169
关键词	coal mining city neural tube defects prevention and control shared component model temporal and spatial analysis
ISSN号	1876-3413
DOI	10.1093/inthealth/ihaa035
通讯作者	Liao, Yilan(liaoyl@lreis.ac.cn)
英文摘要	Background: Neural tube defects (NTDs) are congenital birth defects of the central nervous system that affect 0.5-2 per 1000 pregnancies worldwide. Therefore effective interventions for birth defects, especially NTDs, are very important. Methods: Yuanping City is a coal mining city in Shanxi Province, China, with a high incidence of NTDs. This study evaluates the effects of NTD interventions in this city after adjusting for covariates that characterize the native environment. The number of NTD cases and births for the 18 towns in Yuanping City from 2007 to 2014 were included in the study. A shared-component zero-inflated Poisson regression was applied to analyse the temporal-spatial variance among the incidence rates of NTDs in Yuanping City before and after the interventions. Results: The results showed that existing interventions to mitigate birth defects, such as folic acid supplementation, reduced the incidence of NTDs by 53.5% in coal mining areas in Yuanping City. However, the NTD risk in areas near coal mines, especially unrestored coal mines, was still high, even after the intervention. Conclusions: The government should focus on health hazards related to mining and agricultural production and should provide education and resources to reduce environmental exposure. Reducing environmental risks should be regarded as an early intervention strategy to mitigate birth defects.
资助项目	National Science and Technology Major Project of China[2018ZX10713001] ; Jiangsu Provincial Major Science & Technology Demonstration Project[BE2017749] ; National Natural Science Foundation of China[41101431] ; National Natural Science Foundation of China[41531179] ; National Natural Science Foundation of China[41421001] ; National Natural Science Foundation of China[41471377]
WOS关键词	PERICONCEPTIONAL FOLIC-ACID ; GEOGRAPHIC-VARIATION ; SHANXI PROVINCE ; RISK-FACTOR ; SUPPLEMENTATION ; JOINT ; PREVALENCE ; CANCER ; WOMEN ; MODEL
WOS研究方向	Public, Environmental & Occupational Health
语种	英语
出版者	OXFORD UNIV PRESS
WOS记录号	WOS:000651814800009
资助机构	National Science and Technology Major Project of China ; Jiangsu Provincial Major Science & Technology Demonstration Project ; National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/162918]
专题	中国科学院地理科学与资源研究所
通讯作者	Liao, Yilan
作者单位	1.Jiangsu Ctr Collaborat Innovat Geog Informat Reso, 1 Wenyuan Rd Qixia Dist, Nanjing 210023, Peoples R China 2.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, 11A Datun Rd, Beijing 100101, Peoples R China 3.Sinomaps Press, 3 Baizhifangxi Rd, Beijing 100054, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Ningxu,Liao, Yilan,Ren, Zhoupeng. Evaluating an intervention for neural tube defects in coal mining cites in China: a temporal and spatial analysis[J]. INTERNATIONAL HEALTH,2021,13(2):161-169.
APA	Zhang, Ningxu,Liao, Yilan,&Ren, Zhoupeng.(2021).Evaluating an intervention for neural tube defects in coal mining cites in China: a temporal and spatial analysis.INTERNATIONAL HEALTH,13(2),161-169.
MLA	Zhang, Ningxu,et al."Evaluating an intervention for neural tube defects in coal mining cites in China: a temporal and spatial analysis".INTERNATIONAL HEALTH 13.2(2021):161-169.