Distribution of mercury in serum and blood cells and risk of spontaneous preterm birth: A nested case-control study in China

doi:10.1016/j.ecoenv.2021.112228

	Distribution of mercury in serum and blood cells and risk of spontaneous preterm birth: A nested case-control study in China
	An, Hang 1,4; Wang, Bin 1,4; Li, Zhiyi 2; Jin, Yu 1,4; Ren, Mengyuan 1,4; Yu, Yanxin 3; Zhang, Yali 1,4; Zhang, Le 1,4; Yan, Lailai 5; Li, Zhiwen 1,4
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2021-07-01
卷号	217 页码:7
关键词	Mercury Spontaneous preterm birth Serum Blood cell
ISSN号	0147-6513
DOI	10.1016/j.ecoenv.2021.112228
通讯作者	Ye, Rongwei(yerw@bjmu.edu.cn) ; Li, Kexin(mouselkx_cindy@126.com)
英文摘要	The relationship between maternal mercury (Hg) intake and the risk of spontaneous preterm birth (SPB) remains unclear. We conducted a nested case-control study from a prospective cohort in Shanxi Province, China, to explore their associations. In total, 126 pregnant women with SPB (cases) and 348 controls with term delivery were included. We measured the Hg concentrations in their serum (Hgs) and blood cell (Hgc) fractions and calculated the concentration ratio of Hg in serum to Hg in blood cells (Hgs/c). We found that only the Hgs/c in the case group was slightly higher than that in control group. The OR of Hgs/c associated with SPB risk was 1.57 [95%CI: 0.99-2.46] with adjusting confounders. After stratification by sampling time, the association above was only statistically significant in the first trimester. High Hgs/c may increase the risk of SPB in the first trimester among women with relatively low Hg exposure.
资助项目	National Natural Science Foundation of China[41771527] ; National Natural Science Foundation of China[81673177]
WOS关键词	METHYL MERCURY ; WHOLE-BLOOD ; PREGNANT-WOMEN ; HEAVY-METALS ; EXPOSURE ; PLASMA ; FISH ; LEAD ; ASSOCIATION ; CADMIUM
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
语种	英语
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号	WOS:000649634600009
资助机构	National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/162885]
专题	中国科学院地理科学与资源研究所
通讯作者	Ye, Rongwei; Li, Kexin
作者单位	1.Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China 2.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China 3.Beijing Normal Univ, Sch Environm, Beijing 100875, Peoples R China 4.Peking Univ, Key Lab Reprod Hlth, Natl Hlth Commiss Peoples Republ China, Inst Reprod & Child Hlth, Beijing 100191, Peoples R China 5.Peking Univ, Sch Publ Hlth, Dept Laboratorial Sci & Technol, Beijing 100191, Peoples R China
推荐引用方式 GB/T 7714	An, Hang,Wang, Bin,Li, Zhiyi,et al. Distribution of mercury in serum and blood cells and risk of spontaneous preterm birth: A nested case-control study in China[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2021,217:7.
APA	An, Hang.,Wang, Bin.,Li, Zhiyi.,Jin, Yu.,Ren, Mengyuan.,...&Li, Kexin.(2021).Distribution of mercury in serum and blood cells and risk of spontaneous preterm birth: A nested case-control study in China.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,217,7.
MLA	An, Hang,et al."Distribution of mercury in serum and blood cells and risk of spontaneous preterm birth: A nested case-control study in China".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 217(2021):7.