Characterization of Esophageal Cancer and Its Association with Influencing Factors in Guangzhou City, China

doi:10.3390/ijerph17051498

	Characterization of Esophageal Cancer and Its Association with Influencing Factors in Guangzhou City, China
	Cui, Cheng 1,3; Dong, Hang 2; Ren, Hongyan 1; Lin, Guozhen 2; Zhao, Lu 1,3
刊名	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
	2020-03-01
卷号	17 期号:5 页码:14
关键词	esophageal cancer spatial variation socioeconomic conditions medical resources ageing degree Guangzhou city
DOI	10.3390/ijerph17051498
通讯作者	Ren, Hongyan(renhy@igsnrr.ac.cn) ; Lin, Guozhen(13538761500@126.com)
英文摘要	Epidemiological features of esophageal cancer (EC), as well as their associations with potential influencing factors in a city, have seldom been seldom explored on a fine scale. The EC death cases in Guangzhou city during 2012-2017 were collected to describe the epidemiological characteristics such as EC mortality rate (ECMR) and health-seeking behaviors of deaths. Potential influencing factors, including socioeconomic conditions (population density, gross domestic product density), medical resources, and ageing degree were also gathered for exploring their relationships with the epidemiological characteristics of EC. A total of 2,409 EC deaths were reported during 2012-2017 in Guangzhou with an age-standardized ECMR of 3.18/10(5). The prevalence of EC in Guangzhou was spatially featured and was divided into three regions with obvious differentiated ECMR (ECMR of 6.41/10(5) in region A, ECMR of 5.51/10(5) in region B, ECMR of 2.56/10(5) in region C). The street/town-level ECMR was spatially clustered in Guangzhou city, especially two clusters of streets/towns with high ECMR were highlighted in region A and B respectively. Meanwhile, demographic features including gender gap, death age, temporal interval between diagnosis and death, health-seeking behaviors were remarkably different among the three regions. Moreover, health-seeking behaviors (e.g., the proportion of hospital deaths) of the EC deaths were obviously influenced by medical institution occupancy rate and socioeconomic conditions at street/town level. In addition, the street/town-level ECMR was significantly associated with ageing degree across Guangzhou city (r = 0.466, p < 0.01), especially in region A (r = 0.565, p < 0.01). In contrast, the ECMR in region B was closely related to population density (r = -0.524, p < 0.01) and gross domestic product density (r = -0.511, p < 0.01) when the ageing degree was controlled, while these associations were weak in region C. The epidemiological characteristics of EC in Guangzhou city were spatially featured and potentially associated with socioeconomic conditions, medical resources and ageing degree on a fine scale across Guangzhou city. This study could provide scientific basis for local authorities to implement more targeted EC interventions.
资助项目	National Key Research and Development Program of China[2016YFC1302602]
WOS关键词	SQUAMOUS-CELL CARCINOMA ; CONSUMPTION ; STATISTICS ; MORTALITY
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
语种	英语
出版者	MDPI
WOS记录号	WOS:000522389200038
资助机构	National Key Research and Development Program of China
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/133985]
专题	中国科学院地理科学与资源研究所
通讯作者	Ren, Hongyan; Lin, Guozhen
作者单位	1.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, Beijing 100101, Peoples R China 2.Guangzhou Ctr Dis Control & Prevent, Dept Biostat & Canc Registrat, Guangzhou 510440, Peoples R China 3.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Cui, Cheng,Dong, Hang,Ren, Hongyan,et al. Characterization of Esophageal Cancer and Its Association with Influencing Factors in Guangzhou City, China[J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,2020,17(5):14.
APA	Cui, Cheng,Dong, Hang,Ren, Hongyan,Lin, Guozhen,&Zhao, Lu.(2020).Characterization of Esophageal Cancer and Its Association with Influencing Factors in Guangzhou City, China.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,17(5),14.
MLA	Cui, Cheng,et al."Characterization of Esophageal Cancer and Its Association with Influencing Factors in Guangzhou City, China".INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 17.5(2020):14.