Synthesis, Characterization, and the Antifungal Property of Aminoethyl Chitosan Quaternary Ammonium Salts

doi:10.1002/star.201700266

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Synthesis, Characterization, and the Antifungal Property of Aminoethyl Chitosan Quaternary Ammonium Salts
	Wei, Lijie ; Zhang, Jingjing ; Luan, Fang ; Tan, Wenqiang ; Li, Qing ; Dong, Fang ; Guo, Zhanyong
刊名	STARCH-STARKE
	2018-05
卷号	70 期号:5-6 页码:1700266
关键词	aminoethyl antifungal activity chitosan derivatives quaternary
ISSN号	0038-9056
DOI	10.1002/star.201700266
产权排序	[Wei, Lijie ; Zhang, Jingjing ; Luan, Fang ; Tan, Wenqiang ; Li, Qing ; Dong, Fang ; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China ; [Wei, Lijie ; Zhang, Jingjing ; Luan, Fang ; Tan, Wenqiang ; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
文献子类	Article
英文摘要	Chemical modification of chitosan is one of effective methods to improve the biological activity of chitosan. In this paper, aminoethyl chitosan quaternary ammonium salts, including N-trimetyl quaternary ammonium salt chitosan (TMC), 6-O-(aminoethyl)-2-trimethyl quaternary ammonium chitosan derivative (ONC), and 6-N-(aminoethyl)-2-trimethyl quaternary ammonium chitosan derivative (NNC), are successfully designed, synthesized, and characterized by FT-IR, H-1 NMR, and elemental analyses. Moreover, three kinds of antifungal activities, including B. cinerea Pers., Gibberella zea, and P. asparagi, are all tested by hyphal measurement in vitro. The results show that all chitosan derivatives have better antifungal activities than chitosan. And the antifungal activity decrease in the order: NNC>ONC>TMC>chitosan at 1.0mgmL(-1). Furthermore, the inhibitory indices of NNC and ONC against three kinds of phytopathogens are higher than 75% at 1.0mgmL(-1). Especially, the inhibitory index of NNC against B. cinerea Pers. attain even 90% at 1.0mgmL(-1). These data demonstrate that the aminated chitoan derivative could remarkably improve the antifungal activity of chitosan. On the one hand, the higher positive charge would interact with the anionic components to damage the cell wall. On the other hand, based on the permeability point, the aminoethyl as lipophilic group might pass the oil film into the cell.
WOS关键词	MOLECULAR-WEIGHT CHITOSAN ; ANTIMICROBIAL ACTIVITY ; INULIN DERIVATIVES ; ACID ; ADHESION ; BIOSYNTHESIS ; RECEPTOR ; SPOILAGE ; SULFATE ; DOMAIN
WOS研究方向	Food Science & Technology
语种	英语
WOS记录号	WOS:000431735200018
资助机构	National Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province of China [ZR 2017BD015] ; Yantai Science and Technology Development Plan [2015ZH078] ; Technology Research Funds Projects of Ocean [201505022-3]
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/24478]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室烟台海岸带研究所_污染过程与控制实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wei, Lijie,Zhang, Jingjing,Luan, Fang,et al. Synthesis, Characterization, and the Antifungal Property of Aminoethyl Chitosan Quaternary Ammonium Salts[J]. STARCH-STARKE,2018,70(5-6):1700266.
APA	Wei, Lijie.,Zhang, Jingjing.,Luan, Fang.,Tan, Wenqiang.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and the Antifungal Property of Aminoethyl Chitosan Quaternary Ammonium Salts.STARCH-STARKE,70(5-6),1700266.
MLA	Wei, Lijie,et al."Synthesis, Characterization, and the Antifungal Property of Aminoethyl Chitosan Quaternary Ammonium Salts".STARCH-STARKE 70.5-6(2018):1700266.