Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.

doi:10.1038/ja.2017.109

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.
	Fang, ST ; Yan, BF ; Yang, CY ; Miao, FP ; Ji, NY
刊名	JOURNAL OF ANTIBIOTICS
	2017-11
卷号	70 期号:11 页码:1043-1046
关键词	ANALOGS
ISSN号	0021-8820
DOI	10.1038/ja.2017.109
产权排序	[Fang, Sheng-Tao ; Yang, Cui-Yun ; Miao, Feng-Ping ; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China ; [Yan, Bing-Fei] Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
文献子类	Article
英文摘要	Hymerhabdrin A (1), a diterpenoid possessing a novel 6/6/5 fused-ring skeleton, together with four known sterols were isolated from an intertidal marine sponge Hymerhabdia sp. Their structures were elucidated by extensive spectroscopic methods, and the relative and absolute configurations of 1 were determined by NOESY analysis and electronic circular dichrosim calculations, respectively. Hymerhabdrin A (1) exhibited significant antifouling activity against Balanus amphitrite larval with LC50 (lethal concentration 50) value of 3.6 mu g ml(-1).
WOS关键词	ANALOGS
WOS研究方向	Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000413920300002
资助机构	National Natural Science Foundation of China [21202198]
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/24353]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China; 2.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
推荐引用方式 GB/T 7714	Fang, ST,Yan, BF,Yang, CY,et al. Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.[J]. JOURNAL OF ANTIBIOTICS,2017,70(11):1043-1046.
APA	Fang, ST,Yan, BF,Yang, CY,Miao, FP,&Ji, NY.(2017).Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp..JOURNAL OF ANTIBIOTICS,70(11),1043-1046.
MLA	Fang, ST,et al."Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.".JOURNAL OF ANTIBIOTICS 70.11(2017):1043-1046.