The inhibition effect of cold atmospheric plasma-activated media in cutaneous squamous carcinoma cells

doi:10.2217/fon-2018-0419

CORC > 合肥物质科学研究院 > 中国科学院合肥物质科学研究院 > 中科院等离子体物理研究所

	The inhibition effect of cold atmospheric plasma-activated media in cutaneous squamous carcinoma cells
	Wang, Liyun 2; Yang, Xingyu 2; Yang, Chunjun 2; Gao, Jing 2; Zhao, Ye 4; Cheng, Cheng 3; Zhao, Guoping 5; Liu, Shengxiu 1
刊名	FUTURE ONCOLOGY
	2019-02-01
卷号	15 期号:5 页码:495-505
关键词	CAP-activated media cold atmospheric plasma cutaneous squamous cell carcinoma reactive oxygen species
ISSN号	1479-6694
DOI	10.2217/fon-2018-0419
英文摘要	Aim: This study investigated the effect and mechanism of cold atmospheric plasma (CAP)-activated media on A431 and HaCaT cells. Materials & methods: Phosphate-buffered saline (PBS) and Dulbecco's Modified Eagle's Medium(DMEM) were treated by CAP to get CAP-activated media. A431 and HaCaT were incubated by CAP-activated media for 2h. MTT, Annexin-V and propidium iodide(PI), Western blot and reactive oxygen species (ROS) detection assay were utilized to demonstrate the effect. Results: The CAP-activated media decreased the proliferation of A431 cells in a dose/time-dependent manner. And the CAP-activated media could induce apoptosis in A431 cells. CAP-activated phosphate-buffered saline could increase intracellular ROS level but not CAP-activated DMEM. Conclusion: CAP-activated media could induce apoptosis in A431 cells by production of ROS.
资助项目	foundation of the Second Affiliated Hospital of Anhui Medical University[2015hhjh04] ; National Natural Science Foundation of China[51777206] ; National Natural Science Foundation of China[31600680] ; National Natural Science Foundation of China[81673099] ; National Natural Science Foundation of China[31670860] ; National Natural Science Foundation of China[81602083] ; National Natural Science Foundation of China[31800702] ; Anhui provincial Natural Science Foundation[1608085QH216] ; Anhui provincial Natural Science Foundation[1708085MA13] ; Grants for Scientific Research of BSKY from Anhui Medical University[XJ201505]
WOS关键词	STRESS-ADAPTATION ; SKIN-CANCER ; DIFFERENTIATION ; INACTIVATION ; APOPTOSIS ; CASCADE ; RISK ; CAP
WOS研究方向	Oncology
语种	英语
出版者	FUTURE MEDICINE LTD
WOS记录号	WOS:000458898700005
资助机构	foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; foundation of the Second Affiliated Hospital of Anhui Medical University ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Anhui provincial Natural Science Foundation ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University ; Grants for Scientific Research of BSKY from Anhui Medical University
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/42171]
专题	合肥物质科学研究院_中科院等离子体物理研究所
通讯作者	Yang, Chunjun
作者单位	1.Anhui Med Univ, Affiliated Hosp 1, Dept Dermatol, Hefei, Anhui, Peoples R China 2.Anhui Med Univ, Affiliated Hosp 2, Dept Dermatol, Hefei, Anhui, Peoples R China 3.Chinese Acad Sci, Inst Plasma Phys, Hefei, Anhui, Peoples R China 4.Anhui Med Univ, Teaching & Res Sect Nucl Med, Hefei, Anhui, Peoples R China 5.Chinese Acad Sci, Hefei Inst Phys Sci, Anhui Prov Key Lab Environm Toxicol & Pollut Cont, Hefei, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Wang, Liyun,Yang, Xingyu,Yang, Chunjun,et al. The inhibition effect of cold atmospheric plasma-activated media in cutaneous squamous carcinoma cells[J]. FUTURE ONCOLOGY,2019,15(5):495-505.
APA	Wang, Liyun.,Yang, Xingyu.,Yang, Chunjun.,Gao, Jing.,Zhao, Ye.,...&Liu, Shengxiu.(2019).The inhibition effect of cold atmospheric plasma-activated media in cutaneous squamous carcinoma cells.FUTURE ONCOLOGY,15(5),495-505.
MLA	Wang, Liyun,et al."The inhibition effect of cold atmospheric plasma-activated media in cutaneous squamous carcinoma cells".FUTURE ONCOLOGY 15.5(2019):495-505.