Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress | |
Liang, Jun2; Liu, Jing1,3; Cheng, TingQing1,5; Song, Wencheng1,3,4,5 | |
刊名 | GEOMICROBIOLOGY JOURNAL |
2021-01-18 | |
关键词 | Aspergillus oryzae arsenate comparative transcriptome analysis differentially expressed genes resistance mechanism |
ISSN号 | 0149-0451 |
DOI | 10.1080/01490451.2021.1877854 |
通讯作者 | Cheng, TingQing(chengtq@cmpt.ac.cn) ; Song, Wencheng(wencsong@cmpt.ac.cn) |
英文摘要 | The molecular resistance mechanism of Aspergillus oryzae (A. oryzae) under arsenate (As(V)) stress was investigated by comparative transcriptome analysis. In total, 4911 differentially expressed genes (DEGs) of A. oryzae were detected under As(V) stress, including 2103 up-regulated genes and 2808 down-regulated genes. Genes induced by As(V) were involved in metal ion binding and transportation, redox homeostasis, efflux carrier, DNA repair, volatilization, etc. Moreover, eight genes were selected for qRT-PCR verification, and their trends were consistent with RNA-Seq analysis, which proved that RNA-Seq analysis was efficient and reliable. The results indicated that the extracellular and intracellular synergistic resistance mechanisms contributed to the improvement of A. oryzae resistance to As (V). |
资助项目 | National Natural Science Foundation of China[21876179] ; National Natural Science Foundation of China[22006001] ; Natural Science Foundation of Universities of Anhui Province[KJ2019A0914] ; University Outstanding Young Scientific Research Talent Cultivation Program Project in Anhui Province[gxyq2020091] |
WOS研究方向 | Environmental Sciences & Ecology ; Geology |
语种 | 英语 |
出版者 | TAYLOR & FRANCIS INC |
WOS记录号 | WOS:000612769900001 |
资助机构 | National Natural Science Foundation of China ; Natural Science Foundation of Universities of Anhui Province ; University Outstanding Young Scientific Research Talent Cultivation Program Project in Anhui Province |
内容类型 | 期刊论文 |
源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/119863] |
专题 | 中国科学院合肥物质科学研究院 |
通讯作者 | Cheng, TingQing; Song, Wencheng |
作者单位 | 1.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Hlth & Med Technol, Anhui Prov Key Lab Med Phys & Technol, Hefei, Peoples R China 2.Anhui Univ, Jianghuai Coll, Hefei, Peoples R China 3.Chinese Acad Sci, Hefei Canc Hosp, Hefei, Peoples R China 4.Soochow Univ, Collaborat Innovat Ctr Radiat Med, Jiangsu Higher Educ Inst, Suzhou, Peoples R China 5.Soochow Univ, Sch Radiol & Interdisciplinary Sci, Suzhou, Peoples R China |
推荐引用方式 GB/T 7714 | Liang, Jun,Liu, Jing,Cheng, TingQing,et al. Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress[J]. GEOMICROBIOLOGY JOURNAL,2021. |
APA | Liang, Jun,Liu, Jing,Cheng, TingQing,&Song, Wencheng.(2021).Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress.GEOMICROBIOLOGY JOURNAL. |
MLA | Liang, Jun,et al."Comparative Transcriptome Analysis Providing Resistance Mechanism of Aspergillus oryzae Under Arsenate Stress".GEOMICROBIOLOGY JOURNAL (2021). |
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