Modular Reconfigurable DNA Origami: From Two-Dimensional to Three-Dimensional Structures

doi:10.1002/anie.202010433

	Modular Reconfigurable DNA Origami: From Two-Dimensional to Three-Dimensional Structures
	Liu, Yan 2; Cheng, Jin 2; Fan, Sisi 2; Ge, Huan 3; Luo, Tao 2; Tang, Linlin 2; Ji, Bin 2; Zhang, Chuan 3; Cui, Daxiang 2; Ke, Yonggang 4,5
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2020-10-13
关键词	DNA structures DNA nanotechnology DNA Origami modular transformation nanostructures
ISSN号	1433-7851
DOI	10.1002/anie.202010433
通讯作者	Song, Jie(sjie@sjtu.edu.cn)
英文摘要	DNA origami enables the manipulation of objects at nanoscale, and demonstrates unprecedented versatility for fabricating both static and dynamic nanostructures. In this work, we introduce a new strategy for transferring modular reconfigurable DNA nanostructures from two-dimensional to three-dimensional. A 2D DNA sheet could be modularized into connected parts (e.g., two, three, and four parts in this work), which can be independently transformed between two conformations with a few DNA "trigger" strands. More interestingly, the transformation of the connected 2D modules can lead to the controlled, resettable structural conversion of a 2D sheet to a 3D architecture, due to the constraints induced by the connections between the 2D modules. This new approach can provide an efficient mean for constructing programmable, higher-order, and complex DNA objects, as well as sophisticated dynamic substrates for various applications.
资助项目	National Natural Science Foundation of China[81822024] ; National Natural Science Foundation of China[11761141006] ; Natural Science Foundation of Shanghai, China[19520714100] ; Natural Science Foundation of Shanghai, China[19ZR1475800] ; National Key Research and Development Program of China[2017YFC1200904] ; Project of Shanghai Jiao Tong University[2019QYA03] ; Project of Shanghai Jiao Tong University[YG2017ZD07]
WOS关键词	VISUALIZATION ; NANOMACHINE ; TRANSPORT ; SINGLE
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000578715800001
资助机构	National Natural Science Foundation of China ; Natural Science Foundation of Shanghai, China ; National Key Research and Development Program of China ; Project of Shanghai Jiao Tong University
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/104570]
专题	中国科学院合肥物质科学研究院
通讯作者	Song, Jie
作者单位	1.Univ Chinese Acad Sci, Chinese Acad Sci, Canc Hosp, Inst Canc & Basic Med IBMC, Hangzhou 310022, Zhejiang, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Elect Informat & Elect Engn, Dept Instrument Sci & Engn, Inst Nano Biomed & Engn, Shanghai 200240, Peoples R China 3.Shanghai Jiao Tong Univ, State Key Lab Met Matrix Composites, Frontiers Sci Ctr Transformat Mol, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China 4.Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30322 USA 5.Emory Univ, Atlanta, GA 30322 USA
推荐引用方式 GB/T 7714	Liu, Yan,Cheng, Jin,Fan, Sisi,et al. Modular Reconfigurable DNA Origami: From Two-Dimensional to Three-Dimensional Structures[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2020.
APA	Liu, Yan.,Cheng, Jin.,Fan, Sisi.,Ge, Huan.,Luo, Tao.,...&Song, Jie.(2020).Modular Reconfigurable DNA Origami: From Two-Dimensional to Three-Dimensional Structures.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.
MLA	Liu, Yan,et al."Modular Reconfigurable DNA Origami: From Two-Dimensional to Three-Dimensional Structures".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020).