In vitro antimicrobial effects and mechanism of air plasma-activated water on Staphylococcus aureus biofilm

doi:10.1002/ppap.201900270

	In vitro antimicrobial effects and mechanism of air plasma-activated water on Staphylococcus aureus biofilm
	Xu, Zimu 1,2,3,4; Zhou, Xiaoxia 1; Yang, Weishu 1; Zhang, Yudi 1; Ye, Zhengxin 1; Hu, Shuheng 1; Ye, Chaobin 1; Li, Yunxia 1; Lan, Yan 2,3,4; Shen, Jie 2,3,4
刊名	PLASMA PROCESSES AND POLYMERS
	2020-03-29
关键词	bacteria inactivation biofilm regrowth capacity plasma-activated water (PAW) reactive oxygen species (ROS) Staphylococcus aureus (S aureus) biofilm
ISSN号	1612-8850
DOI	10.1002/ppap.201900270
通讯作者	Hu, Shuheng(shuheng.hu@163.com) ; Cheng, Cheng(chengcheng@ipp.ac.cn)
英文摘要	The deactivation effects and mechanism of plasma-activated water (PAW) against Staphylococcus aureus biofilm and the inhibitory effect on the biofilm regrowth capacity for the surviving S. aureus post PAW treatment were investigated in vitro. Systematic measurements on bacterial cultivability, metabolic capacity, membrane integrity and intracellular reactive oxygen species (ROS) concentration under two different experimental categories were carried out after PAW treatment. Considerable deactivation effects were discovered on biofilm S. aureus on both prolonging the PAW inducement or treatment time. The rising concentration of intracellular ROS and the PAW-contained RS might exert synergistic effects in deactivating the biofilm S. aureus. Moreover, the biomass, bacterial cultivability and metabolic capacity of the regrown S. aureus biofilm all significantly declined along with the increasing PAW inducement or treatment time. Therefore, except for the short-term rapid inactivation effects on the biofilm, the PAW treatment could also exert long-term inhibitory effects on the regeneration of S. aureus biofilm.
资助项目	National Natural Science Foundation of China[51777206] ; National Natural Science Foundation of China[51807046] ; National Natural Science Foundation of China[51877208] ; Specialized Research Fund for the Doctoral Program of Hefei University of Technology[JZ2017HGBZ0944] ; Foundation of Anhui Province Key Laboratory of Medical Physics and Technology[LMPT2017Y7BP0U1581]
WOS关键词	ATMOSPHERIC-PRESSURE PLASMA ; NONTHERMAL PLASMA ; PSEUDOMONAS-AERUGINOSA ; DISCHARGE PLASMA ; BACTERIAL INACTIVATION ; ESCHERICHIA-COLI ; ARGON PLASMA ; EFFICACY ; JET ; SUSCEPTIBILITY
WOS研究方向	Physics ; Polymer Science
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000522059000001
资助机构	National Natural Science Foundation of China ; Specialized Research Fund for the Doctoral Program of Hefei University of Technology ; Foundation of Anhui Province Key Laboratory of Medical Physics and Technology
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/103557]
专题	中国科学院合肥物质科学研究院
通讯作者	Hu, Shuheng; Cheng, Cheng
作者单位	1.Hefei Univ Technol, Sch Resources & Environm Engn, Hefei 230009, Anhui, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, Ctr Med Phys & Technol, Hefei, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Anhui Prov Key Lab Med Phys & Technol, Hefei, Peoples R China 4.Chinese Acad Sci, Inst Plasma Phys, Hefei 230031, Anhui, Peoples R China 5.Anhui Agr Univ, Sch Forestry & Landscape Architecture, Hefei, Peoples R China
推荐引用方式 GB/T 7714	Xu, Zimu,Zhou, Xiaoxia,Yang, Weishu,et al. In vitro antimicrobial effects and mechanism of air plasma-activated water on Staphylococcus aureus biofilm[J]. PLASMA PROCESSES AND POLYMERS,2020.
APA	Xu, Zimu.,Zhou, Xiaoxia.,Yang, Weishu.,Zhang, Yudi.,Ye, Zhengxin.,...&Cheng, Cheng.(2020).In vitro antimicrobial effects and mechanism of air plasma-activated water on Staphylococcus aureus biofilm.PLASMA PROCESSES AND POLYMERS.
MLA	Xu, Zimu,et al."In vitro antimicrobial effects and mechanism of air plasma-activated water on Staphylococcus aureus biofilm".PLASMA PROCESSES AND POLYMERS (2020).