On the flow characteristics in different carotid arteries

doi:10.1063/5.0022092

CORC > 力学研究所 > 中国科学院力学研究所 > 非线性力学国家重点实验室

	On the flow characteristics in different carotid arteries
	Chen Y(陈与)3,4; Yang XL(杨晓雷)2,3; Iskander AJ 1; Wang P 4
刊名	PHYSICS OF FLUIDS
	2020-10-01
卷号	32 期号:10 页码:17
ISSN号	1070-6631
DOI	10.1063/5.0022092
通讯作者	Yang, Xiaolei(xyang@imech.ac.cn)
英文摘要	Hemodynamics plays an important role in the cause of atherosclerotic disease. In this work, we simulated the flow fields in six human carotids using the sharp-interface immersed boundary method. We compare the axial velocity, the secondary flow, the vortex structures, the area with reversed flows, and the standard deviation of velocity fluctuations for different carotids. The computed results show similarities among different carotids for the overall pattern of different flow characteristics. More importantly, differences are observed in terms of the details of the area of the reversed flow region, the size and shape of the region dominated by reversed flows, and the length of time with reversed flow or dominated by secondary flows, which are strongly correlated with the formation of plaques. Further analysis shows that patient-specific features of the carotid geometry, e.g., the flare and proximal curvature of the carotid, have significant effects on these flow characteristics. This suggests that a patient-specific program is needed for the prevention and treatment of atherosclerosis.
分类号	一类/力学重要期刊
资助项目	NSFC Basic Science Center Program for Multiscale Problems in Nonlinear Mechanics[11988102]
WOS关键词	WALL SHEAR-STRESS ; BLOOD-FLOW ; BIFURCATION GEOMETRY ; NUMERICAL-SIMULATION ; PULSATILE FLOW ; WAVE-FORMS ; MODEL ; ATHEROSCLEROSIS ; ASSOCIATION ; PREDICTOR
WOS研究方向	Mechanics ; Physics
语种	英语
WOS记录号	WOS:000582121800001
资助机构	NSFC Basic Science Center Program for Multiscale Problems in Nonlinear Mechanics
其他责任者	Yang, Xiaolei
内容类型	期刊论文
源URL	[http://dspace.imech.ac.cn/handle/311007/85387]
专题	力学研究所_非线性力学国家重点实验室
作者单位	1.Westchester Med Ctr, Dept Anesthesiol, 100 Woods Rd, Valhalla, NY 10595 USA 2.Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China; 3.Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China; 4.Lanzhou Univ, Dept Mech, Lanzhou 730000, Peoples R China;
推荐引用方式 GB/T 7714	Chen Y,Yang XL,Iskander AJ,et al. On the flow characteristics in different carotid arteries[J]. PHYSICS OF FLUIDS,2020,32(10):17.
APA	陈与,杨晓雷,Iskander AJ,&Wang P.(2020).On the flow characteristics in different carotid arteries.PHYSICS OF FLUIDS,32(10),17.
MLA	陈与,et al."On the flow characteristics in different carotid arteries".PHYSICS OF FLUIDS 32.10(2020):17.