Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings

doi:10.1021/acs.nanolett.9b03232

CORC > 力学研究所 > 中国科学院力学研究所 > 高温气体动力学国家重点实验室

	Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings
	Gao L 4,5; Wang JF 1,4; Guan SL 4,5; Du MD 3,4,5; Wu K(吴坤)2; Xu K 4,5; Zou L 4,5; Tian HH 4; Fang Y 4,5,6
刊名	NANO LETTERS
	2019-11-01
卷号	19 期号:11 页码:8032-8039
关键词	flexible microelectrode magnetic actuation nanoscale roughness neural recording inflammatory response
ISSN号	1530-6984
DOI	10.1021/acs.nanolett.9b03232
通讯作者	Fang, Ying(fangy@nanoctr.cn)
英文摘要	Implantable microelectrodes that can be remotely actuated via external fields are promising tools to interface with biological systems at a high degree of precision. Here, we report the development of flexible magnetic microelectrodes (FM mu Es) that can be remotely actuated by magnetic fields. The FM mu Es consist of flexible microelectrodes integrated with dielectrically encapsulated FeNi (iron-nickel) alloy microactuators. Both magnetic torque- and force-driven actuation of the EM mu Es have been demonstrated. Nanoplatinum-coated FM mu Es have been applied for in vivo recordings of neural activities from peripheral nerves and cerebral cortex of mice. Moreover, owing to their ultrasmall sizes and mechanical compliance with neural tissues, chronically implanted FM mu Es elicited greatly reduced neuronal cell loss in mouse brain compared to conventional stiff probes. The FM mu Es open up a variety of new opportunities for electrically interfacing with biological systems in a controlled and minimally invasive manner.
分类号	一类
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDB32030100] ; National Natural Science Foundation of China[21790393] ; National Natural Science Foundation of China[21673057] ; Frontier Research Program of the Chinese Academy of Sciences[QYZDB-SSW-SLH044] ; Fabrication Lab at NCNST
WOS关键词	TISSUE-RESPONSE ; BRAIN-TISSUE ; ELECTRODES ; SYSTEM ; MICROROBOTS ; POTENTIALS ; IMPLANTS ; CORTEX ; CELLS ; FILMS
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种	英语
WOS记录号	WOS:000497259300055
资助机构	Strategic Priority Research Program of the Chinese Academy of Sciences ; National Natural Science Foundation of China ; Frontier Research Program of the Chinese Academy of Sciences ; Fabrication Lab at NCNST
其他责任者	Fang, Ying
内容类型	期刊论文
源URL	[http://dspace.imech.ac.cn/handle/311007/81216]
专题	力学研究所_高温气体动力学国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Labs Transducer Technol, Beijing 100190, Peoples R China; 2.Chinese Acad Sci, Inst Mech, State Key Lab High Temp Gas Dynam, Beijing 100190, Peoples R China; 3.Aalto Univ, Dept Elect & Nanoengn, FI-00076 Espoo, Finland 4.Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China; 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 6.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China;
推荐引用方式 GB/T 7714	Gao L,Wang JF,Guan SL,et al. Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings[J]. NANO LETTERS,2019,19(11):8032-8039.
APA	Gao L.,Wang JF.,Guan SL.,Du MD.,吴坤.,...&Fang Y.(2019).Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings.NANO LETTERS,19(11),8032-8039.
MLA	Gao L,et al."Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings".NANO LETTERS 19.11(2019):8032-8039.