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	Diversity-oriented synthesis of natural product-like libraries
	Liu Gang; Li Yulin; Nan Fajun
刊名	PROGRESS IN CHEMISTRY
	2006-06
卷号	18期号:6页码:734-742
关键词	diversity-oriented synthesis (DOS) natural product-like libraries target-oriented synthesis
ISSN号	1005-281X
文献子类	Article
英文摘要	Natural products provide the most important sources of lead compounds in drug discovery. With the development of high-throughput screening (HTS) technology and in depth studies in chemical biology, exploring pharmaceutically relevant chemical space of natural products is vital. Employing diversity-oriented synthesis (DOS) to construct skeletally complex natural product-like libraries and using it in the studies of chemical biology and lead discovery is becoming a tendency. The development of exceptionally efficient, stereoselective, and chemoselective reactions that can be applied to a wide range of substrates play key roles.
WOS关键词	SOLID-PHASE SYNTHESIS ; SMALL ORGANIC-MOLECULES ; COMBINATORIAL SYNTHESIS ; DRUG DISCOVERY ; PRIVILEGED STRUCTURES ; BENZOPYRAN LIBRARIES ; CHEMICAL GENETICS ; CLICK CHEMISTRY ; CELL-CYCLE ; INHIBITORS
WOS研究方向	Chemistry
语种	中文
CSCD记录号	CSCD:2505355
出版者	CHINESE ACAD SCIENCES
WOS记录号	WOS:000238548200007
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/273584]
专题	国家新药筛选中心
通讯作者	Liu Gang
作者单位	1.Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Chinese Natl Ctr Drug Screening, Shanghai 201203, Peoples R China 2.Lanzhou Univ, Inst Organ Chem, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Liu Gang,Li Yulin,Nan Fajun. Diversity-oriented synthesis of natural product-like libraries[J]. PROGRESS IN CHEMISTRY,2006,18(6):734-742.
APA	Liu Gang,Li Yulin,&Nan Fajun.(2006).Diversity-oriented synthesis of natural product-like libraries.PROGRESS IN CHEMISTRY,18(6),734-742.
MLA	Liu Gang,et al."Diversity-oriented synthesis of natural product-like libraries".PROGRESS IN CHEMISTRY 18.6(2006):734-742.

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