Perspectives in endogenous retroviruses: biological functions and implications in cancer | |
Wu Yuanfeng; Luan Yang | |
刊名 | Chinese Bulletin of Life Sciences
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2014 | |
卷号 | 26期号:9页码:955-961 |
关键词 | endogenous retrovirus function placental development cancer biomarker |
ISSN号 | 1004-0374 |
其他题名 | 内源性逆转录病毒生物学功能及与肿瘤的关系 |
文献子类 | Review |
英文摘要 | Endogenous retrovirus (ERV) sequences represent relics of ancestral exogenous retrovirus infection of germ-line cells during evolution. ERVs were once thought to be junk DNA sequences. However, a growing number of studies have shown that ERVs play important physiological roles, including mammalian placental development and suppression of infection of exogenous retrovirus. In addition, ERVs have been implicated in certain diseases such as cancer. This review, focusing on the human and mouse ERVs, summarized the biological functions of ERVs as well as its relationship with cancer. |
资助项目 | 国家自然科学基金项目[00000000] |
WOS研究方向 | General & Internal Medicine ; Oncology (provided by Clarivate Analytics) |
语种 | 中文 |
CSCD记录号 | CSCD:5241115 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/269315] ![]() |
专题 | 药物安全性评价中心 |
作者单位 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. |
推荐引用方式 GB/T 7714 | Wu Yuanfeng,Luan Yang. Perspectives in endogenous retroviruses: biological functions and implications in cancer[J]. Chinese Bulletin of Life Sciences,2014,26(9):955-961. |
APA | Wu Yuanfeng,&Luan Yang.(2014).Perspectives in endogenous retroviruses: biological functions and implications in cancer.Chinese Bulletin of Life Sciences,26(9),955-961. |
MLA | Wu Yuanfeng,et al."Perspectives in endogenous retroviruses: biological functions and implications in cancer".Chinese Bulletin of Life Sciences 26.9(2014):955-961. |
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