Perspectives in endogenous retroviruses: biological functions and implications in cancer

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	Perspectives in endogenous retroviruses: biological functions and implications in cancer
	Wu Yuanfeng; Luan Yang
刊名	Chinese Bulletin of Life Sciences
	2014
卷号	26 期号:9 页码:955-961
关键词	endogenous retrovirus function placental development cancer biomarker
ISSN号	1004-0374
其他题名	内源性逆转录病毒生物学功能及与肿瘤的关系
文献子类	Review
英文摘要	Endogenous retrovirus (ERV) sequences represent relics of ancestral exogenous retrovirus infection of germ-line cells during evolution. ERVs were once thought to be junk DNA sequences. However, a growing number of studies have shown that ERVs play important physiological roles, including mammalian placental development and suppression of infection of exogenous retrovirus. In addition, ERVs have been implicated in certain diseases such as cancer. This review, focusing on the human and mouse ERVs, summarized the biological functions of ERVs as well as its relationship with cancer.
资助项目	国家自然科学基金项目[00000000]
WOS研究方向	General & Internal Medicine ; Oncology (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:5241115
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/269315]
专题	药物安全性评价中心
作者单位	Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式 GB/T 7714	Wu Yuanfeng,Luan Yang. Perspectives in endogenous retroviruses: biological functions and implications in cancer[J]. Chinese Bulletin of Life Sciences,2014,26(9):955-961.
APA	Wu Yuanfeng,&Luan Yang.(2014).Perspectives in endogenous retroviruses: biological functions and implications in cancer.Chinese Bulletin of Life Sciences,26(9),955-961.
MLA	Wu Yuanfeng,et al."Perspectives in endogenous retroviruses: biological functions and implications in cancer".Chinese Bulletin of Life Sciences 26.9(2014):955-961.