Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity | |
Yang, Wen-zhi2; Hu, Ying1; Wu, Wan-ying2![]() ![]() | |
刊名 | PHYTOCHEMISTRY
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2014-10 | |
卷号 | 106页码:7-24 |
关键词 | Panax genus Panax ginseng Panax quinquefolius Panax notoginseng Araliaceae Saponins Chemical diversity Subtype classification |
ISSN号 | 0031-9422 |
DOI | 10.1016/j.phytochem.2014.07.012 |
文献子类 | Review |
英文摘要 | The Panax genus is a crucial source of natural medicines that has benefited human health for a long time. Three valuable medicinal herbs, namely Panax ginseng, Panax quinquefolius, and Panax notoginseng, have received considerable interest due to their extensive application in clinical therapy, healthcare products, and as foods and food additives world-wide. Panax species are known to contain abundant levels of saponins, also dubbed ginsenosides, which refer to a series of dammarane or oleanane type triterpenoid glycosides. These saponins exhibit modulatory effects to the central nervous system and beneficial effects to patients suffering from cardiovascular diseases, and also have anti-diabetic and anti-tumor properties. To the end of 2012, at least 289 saponins were reported from eleven different Panax species. This comprehensive review describes the advances in the phytochemistry of the genus Panax for the period 1963-2012, based on the 134 cited references. The reported saponins can be classified into protopanaxadiol, protopanaxatriol, octillol, oleanolic acid, C17 side-chain varied, and miscellaneous subtypes, according to structural differences in sapogenins. The investigational history of Panax is also reviewed, with special attention being paid to the structural features of the six different subtypes, together with their H-1 and C-13 NMR spectroscopic characteristics which are useful for determining their structures and absolute configuration. (C) 2014 Elsevier Ltd. All rights reserved. |
资助项目 | Program for New Century Excellent Talents in University from China Ministry of Education[BMU20110269] |
WOS关键词 | DAMMARANE-TYPE SAPONINS ; KOREAN RED GINSENG ; HEAT-PROCESSED GINSENG ; ORIENTAL PLANT DRUGS ; F H. CHEN ; FLOWER-BUDS ; TRITERPENE SAPONINS ; QUINQUEFOLIUM-L ; CA MEYER ; BIOACTIVE SAPONINS |
WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
语种 | 英语 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS记录号 | WOS:000342258600001 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/276890] ![]() |
专题 | 上海中药现代化研究中心 |
通讯作者 | Ye, Min |
作者单位 | 1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China 2.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; |
推荐引用方式 GB/T 7714 | Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,et al. Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity[J]. PHYTOCHEMISTRY,2014,106:7-24. |
APA | Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,Ye, Min,&Guo, De-an.(2014).Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity.PHYTOCHEMISTRY,106,7-24. |
MLA | Yang, Wen-zhi,et al."Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity".PHYTOCHEMISTRY 106(2014):7-24. |
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