Biotransformation of patchoulol by Cunninghamella echinulata var. elegans

doi:10.1016/j.fitote.2016.01.001

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	Biotransformation of patchoulol by Cunninghamella echinulata var. elegans
	Xu, Fangfang 3; Liao, Kangsheng 3; Liu, Yuhong 2; Zhang, Zhenbiao 2; Guo, Dean1 ; Su, Ziren 2; Liu, Bo 3
刊名	FITOTERAPIA
	2016-03
卷号	109 页码:201-205
关键词	Biotransformation Patchoulol Cunninghamella echinulata var. elegans X-ray crystallography
ISSN号	0367-326X
DOI	10.1016/j.fitote.2016.01.001
文献子类	Article
英文摘要	Biocatalysis of patchoulol (PA) was performed by the fungus Cunninghamella echinulata var. elegans. Eight metabolites (1-8) including four new compounds were obtained, and their structures were elucidated as (5R,8S)-5,8 dihydroxypatchoulol (1), (5R,9R)-5,9 dihydroxypatchoulol (2), (6S, 9S) -6,9 dihydroxypatchoulol (3), and (4R*) -4 hydroxypatchoulol (4) by spectroscopic analysis. The absolute configuration of 1 was determined by single crystal X-ray diffraction. (C) 2016 Elsevier B.V. All rights reserved.
资助项目	National Natural Science Foundation of China[81202398] ; Specific Research Construction Project of National Clinical Research Base of TCM[JDZX2012010]
WOS关键词	POGOSTEMONIS HERBA ; ARTEMISININ
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000372685400032
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/276116]
专题	上海中药现代化研究中心
通讯作者	Guo, Dean; Su, Ziren; Liu, Bo
作者单位	1.Chinese Acad Sci, Natl Engn Lab TCM Standardizat Technol, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, 501 Haike Rd, Shanghai 201203, Peoples R China 2.Guangzhou Univ Chinese Med, Coll Chinese Med, Guangzhou 510006, Guangdong, Peoples R China; 3.Guangzhou Univ Chinese Med, Affiliated Hosp 2, Guangdong Prov Acad Chinese Med Sci, Guangzhou 510006, Guangdong, Peoples R China;
推荐引用方式 GB/T 7714	Xu, Fangfang,Liao, Kangsheng,Liu, Yuhong,et al. Biotransformation of patchoulol by Cunninghamella echinulata var. elegans[J]. FITOTERAPIA,2016,109:201-205.
APA	Xu, Fangfang.,Liao, Kangsheng.,Liu, Yuhong.,Zhang, Zhenbiao.,Guo, Dean.,...&Liu, Bo.(2016).Biotransformation of patchoulol by Cunninghamella echinulata var. elegans.FITOTERAPIA,109,201-205.
MLA	Xu, Fangfang,et al."Biotransformation of patchoulol by Cunninghamella echinulata var. elegans".FITOTERAPIA 109(2016):201-205.