Drug discovery based on classic natural products | |
Hu, Li-hong; Xu, Ji-qing | |
2009-01 | |
卷号 | 44 |
期号 | 1 |
页码 | 11-8 |
英文摘要 | We think the strategy of classic natural product-based drug discovery will be an effective way for us to develop new drugs with independent intellectual property. The strategy includes: to study the molecular mechanism of action of classic natural product with chemical genetics and chemical biology approaches firstly; then establish the proper in vitro bioassay or bioassay system based on its molecular mechanism for their pharmacodynamic evaluation; finally, study their structure-activity, structure-toxicity and structure-ADME properties with medicinal chemistry. |
会议录 | Yao xue xue bao = Acta pharmaceutica Sinica
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文献子类 | Meeting Abstract;Article;Review |
语种 | 中文 |
内容类型 | 会议论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/266949] ![]() |
专题 | 上海中药现代化研究中心 |
通讯作者 | Hu, Li-hong |
作者单位 | Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China |
推荐引用方式 GB/T 7714 | Hu, Li-hong,Xu, Ji-qing. Drug discovery based on classic natural products[C]. 见:. |
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