Drug discovery based on classic natural products

	Drug discovery based on classic natural products
	Hu, Li-hong; Xu, Ji-qing
	2009-01
卷号	44
期号	1
页码	11-8
英文摘要	We think the strategy of classic natural product-based drug discovery will be an effective way for us to develop new drugs with independent intellectual property. The strategy includes: to study the molecular mechanism of action of classic natural product with chemical genetics and chemical biology approaches firstly; then establish the proper in vitro bioassay or bioassay system based on its molecular mechanism for their pharmacodynamic evaluation; finally, study their structure-activity, structure-toxicity and structure-ADME properties with medicinal chemistry.
会议录	Yao xue xue bao = Acta pharmaceutica Sinica
文献子类	Meeting Abstract;Article;Review
语种	中文
内容类型	会议论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266949]
专题	上海中药现代化研究中心
通讯作者	Hu, Li-hong
作者单位	Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
推荐引用方式 GB/T 7714	Hu, Li-hong,Xu, Ji-qing. Drug discovery based on classic natural products[C]. 见:.