Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation

doi:10.12688/f1000research.6007.1

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	Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation
	Liu, Rongxia 3,4; Heiss, Elke H 1; Guo, Dean2 ; Dirsch, Verena M 1; Atanasov, Atanas G 1
刊名	F1000Research
	2015
卷号	4 页码:26
ISSN号	2046-1402
DOI	10.12688/f1000research.6007.1
文献子类	Article
英文摘要	Accelerated vascular smooth muscle cell (VSMC) proliferation is implied in cardiovascular disease and significantly contributes to vessel lumen reduction following surgical interventions such as percutaneous transluminal coronary angioplasty or bypass surgery. Therefore, identification and characterization of compounds and mechanisms able to counteract VSMC proliferation is of potential therapeutic relevance. This work reveals the anti-proliferative effect of the natural product capsaicin from Capsicum spp. by quantification of metabolic activity and DNA synthesis in activated VSMC. The observed in vitro activity profile of capsaicin warrants further research on its mechanism of action and potential for therapeutic application.
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266329]
专题	上海中药现代化研究中心
作者单位	1.Department of Pharmacognosy, University of Vienna, Vienna, Austria; 2.Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China 3.Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; 4.Department of Pharmacognosy, University of Vienna, Vienna, Austria ;
推荐引用方式 GB/T 7714	Liu, Rongxia,Heiss, Elke H,Guo, Dean,et al. Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation[J]. F1000Research,2015,4:26.
APA	Liu, Rongxia,Heiss, Elke H,Guo, Dean,Dirsch, Verena M,&Atanasov, Atanas G.(2015).Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation.F1000Research,4,26.
MLA	Liu, Rongxia,et al."Capsaicin from chili ( Capsicum spp.) inhibits vascular smooth muscle cell proliferation".F1000Research 4(2015):26.