A novel water-soluble beta-D-glucan isolated from the spores of Ganoderma lucidum | |
Dong, Qun1; Wang, Ying1; Shi, Lei1; Yao, Jian1; Li, Jie1; Ma, Fangli2; Ding, Kan1![]() | |
刊名 | CARBOHYDRATE RESEARCH
![]() |
2012-05-15 | |
卷号 | 353页码:100-105 |
关键词 | Ganoderma lucidum beta-(1 -> 6)-Glucan Polysaccharide Structure |
ISSN号 | 0008-6215 |
DOI | 10.1016/j.carres.2012.02.029 |
文献子类 | Article |
英文摘要 | Ganoderma lucidum is an edible and medicinal mushroom used widely in East Asia. In recent years, its spores have been used as a supplement in combination with other forms of antitumor therapies. The cell wall of Ganoderma lucidum spores contains a high amount of polysaccharides. In this study, a neutral polysaccharide, GLSA50-1B, was isolated from sporoderm-broken spores of Ganoderma lucidum, by hot-water extraction, graded ethanol precipitation, anion-exchange chromatography, and gel permeation chromatography. Using sugar compositional analysis, methylation analysis, partial acid hydrolysis, acetolysis, and NMR and ESI-MS spectroscopy, GLSA50-1B was elucidated to be a novel beta-D-glucan featured by a 1,6-linked beta-D-Glcp backbone with different length of branches consisting of terminal and 1,4-linked Glcp residues, attached to O-4 of alternative Glc residues in the backbone. (C) 2012 Elsevier Ltd. All rights reserved. |
资助项目 | National High Technology Project (863)[2007AA10Z341] ; Key New Drug Creation and Manufacturing Program[2009ZX09501-011] ; Key New Drug Creation and Manufacturing Program[2009ZX09103-071] ; Key New Drug Creation and Manufacturing Program[2009ZX09301-001] |
WOS关键词 | STRUCTURAL-CHARACTERIZATION ; FR. KARST ; POLYSACCHARIDE ; CELLS ; CYTOKINES ; FEATURES ; VEGF ; MICE |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
语种 | 英语 |
出版者 | ELSEVIER SCI LTD |
WOS记录号 | WOS:000304053900014 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/278076] ![]() |
专题 | 药理学第三研究室 |
通讯作者 | Dong, Qun |
作者单位 | 1.Chinese Acad Sci & Infinitus, Shanghai Inst Mat Med, Glycobiol & Glycochem Lab, Shanghai 201203, Peoples R China; 2.Lee Kum Kee Hlth Prod Grp Ltd, Hong Kong, Hong Kong, Peoples R China |
推荐引用方式 GB/T 7714 | Dong, Qun,Wang, Ying,Shi, Lei,et al. A novel water-soluble beta-D-glucan isolated from the spores of Ganoderma lucidum[J]. CARBOHYDRATE RESEARCH,2012,353:100-105. |
APA | Dong, Qun.,Wang, Ying.,Shi, Lei.,Yao, Jian.,Li, Jie.,...&Ding, Kan.(2012).A novel water-soluble beta-D-glucan isolated from the spores of Ganoderma lucidum.CARBOHYDRATE RESEARCH,353,100-105. |
MLA | Dong, Qun,et al."A novel water-soluble beta-D-glucan isolated from the spores of Ganoderma lucidum".CARBOHYDRATE RESEARCH 353(2012):100-105. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论