Development and application of component-based Chinese medicine theory

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 上海药物代谢研究中心

	Development and application of component-based Chinese medicine theory
	Zhang Junhua 5; Fan Guanwei 5; Zhang Han 5; Fan Xiaohui 1; Wang Yi 1; Liu Limei 2; Li Chuan 3; Gao Yue 4; Gao Xiumei 5; Zhang Boli 5
刊名	China Journal of Chinese Materia Medica
	2017
卷号	42 期号:21 页码:4054-4058
关键词	component-based Chinese medicine compatibility of Chinese medicinal prescription efficacy-oriented compatibility modernization of Chinese medicine
ISSN号	1001-5302
其他题名	组分中药理论的发展与应用
文献子类	Article
英文摘要	Traditional Chinese medicine (TCM) prescription is the main therapies for disease prevention and treatment in Chinese medicine.Following the guidance of the theory of TCM and developing drug by composing prescriptions of TCM materials and pieces, it is a traditional application mode of TCM, and still widely used in clinic.TCM prescription has theoretical advantages and rich clinical application experience in dealing with multi-factor complex diseases, but scientific research is relatively weak.The lack of scientific cognition of the effective substances and mechanism of Chinese medicine leads to insufficient understanding of the efficacy regularity, which affects the stability of effect and hinders the improvement of quality of Chinese medicinal products.Component-based Chinese medicine (CCM) is an innovation based on inheritance, which breaks through the tradition of experience-based prescription and realize the transformation of compatibility from herbal pieces to components.CCM is an important achievement during the research process of modernization of Chinese medicine.Underthesupportof three national "973" projects, in order to reveal the scientific connotation of the prescription compatibility theory and develop innovative Chinese drugs, we have launched theoretical innovation and technological innovation around the "two relatively clear", and opened up the research field of CCM. CCM is an innovation based on inheritance, breaking through the tradition of experience based prescription, and realizing the transformation from compatibility of herbal pieces to component compatibility, which is an important achievement of the modernization of traditional Chinese medicine.In the past more than 10 years, with the deepening of research and the expansion of application, the theory and methods of CCM and efficacy-oriented compatibility have been continuously improved.The value of CCM is not only in developing new drug, more important is to build a communication bridge between traditional Chinese medicine and modern science and construct the system of key technologies which meet the need of innovation and development of TCM.This paper focused on the research progress, related concepts and technology development of CCM, as well as its application prospect inthe theory research of Chinesemedicine, development of innovative Chinese drugs, secondary development of Chinese patent medicine and upgrading of pharmaceutical technology.
资助项目	国家重点基础研究发展计划 (973)项目[00000000]
WOS研究方向	General & Internal Medicine (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:6134388
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/269188]
专题	上海药物代谢研究中心科研与新药推进处
作者单位	1.Pharmaceutical Informatics Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China.; 2.Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.; 3.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; 4.Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China. 5.Institute of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China.;
推荐引用方式 GB/T 7714	Zhang Junhua,Fan Guanwei,Zhang Han,et al. Development and application of component-based Chinese medicine theory[J]. China Journal of Chinese Materia Medica,2017,42(21):4054-4058.
APA	Zhang Junhua.,Fan Guanwei.,Zhang Han.,Fan Xiaohui.,Wang Yi.,...&Zhang Boli.(2017).Development and application of component-based Chinese medicine theory.China Journal of Chinese Materia Medica,42(21),4054-4058.
MLA	Zhang Junhua,et al."Development and application of component-based Chinese medicine theory".China Journal of Chinese Materia Medica 42.21(2017):4054-4058.