Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues

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	Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues
	ZHOU Maojin 2; CHEN Xiaoyan1 ; ZHONG Dafang1
刊名	Acta Pharmaceutica Sinica
	2007
卷号	42 期号:5 页码:520-524
关键词	trans-resveratrol-3-O-glucoside incubation metabolism
ISSN号	0513-4870
其他题名	反式白藜芦醇葡糖苷在大鼠组织中的体外代谢研究
文献子类	Article
英文摘要	To study the metabolism of trans-resveratrol-3-O-glueoside （TRG） in vitro in rat tissues, the incubation with cell-free extracts from rat stomach, duodenum, jejunum, ileum and liver was performed, separately. After TRG was incubated with the tissue extracts at 37℃ for up to 90 min, the deglycosylation of TRG was （3.50 0.24） % for stomach, （65.7 5.94） % for duodenum, （83.5 6. 43）% for jejunum, （77.6 6.26）% for ileum and （9.62 1.21）% for liver, separately. It was observed that the small intestine extracts were more active in deglycosylation of TRG than the liver extract, which suggested that the small intestine mucosa played an important role in deglycosylation of TRG. It was assumed that the deglycosylation of TRG was catalyzed by beta-glucosidase in small intestine mucosa.
资助项目	国家自然科学基金资助项目[00000000]
WOS研究方向	Pharmacology & Pharmacy (provided by Clarivate Analytics)
语种	中文
CSCD记录号	CSCD:2877176
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/268163]
专题	上海药物代谢研究中心
作者单位	1.Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, China. 2.Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, China.;
推荐引用方式 GB/T 7714	ZHOU Maojin,CHEN Xiaoyan,ZHONG Dafang. Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues[J]. Acta Pharmaceutica Sinica,2007,42(5):520-524.
APA	ZHOU Maojin,CHEN Xiaoyan,&ZHONG Dafang.(2007).Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues.Acta Pharmaceutica Sinica,42(5),520-524.
MLA	ZHOU Maojin,et al."Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues".Acta Pharmaceutica Sinica 42.5(2007):520-524.