LC-MS在中草药药代研究的应用(英文)

	LC-MS在中草药药代研究的应用(英文)
	李川
	2006-10-01
关键词	MS LC-MS
页码	2
英文摘要	Unlike synthetic drugs, herbal remedies are complex mixtures. However, monitoring the blood levels of known active constituents, representative markers, or major chemical constituents in a botanical drug product is strongly encouraged by the Chinese SFDA. as well as the U.S. FDA, because data on absorption and disposition of the chemicals are very relevant to pharmacological and other beneficial effects of the medicine. The pharmacokinetic measurements for phytomedicines often involve the assay of multiple analytes from complex biomatrix samples, which should not be made easily and the data generated may not be as reliable as is commonly perceived. Liquid chromatographic mass spectrometry (LC-MS or LC-MS/MS) is the current method of choice to support pharmacokinetic evaluation of herbal remedies. However, coeluting
会议录	第八次全国药物与化学异物代谢学术会议论文摘要
文献子类	Article
语种	英语
内容类型	会议论文
源URL	[http://119.78.100.183/handle/2S10ELR8/267533]
专题	上海药物代谢研究中心
作者单位	中国科学院上海药物研究所,上海药物代谢研究中心,上海 201203, 中国.
推荐引用方式 GB/T 7714	李川. LC-MS在中草药药代研究的应用(英文)[C]. 见:.