Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana

doi:10.1007/s13659-014-0020-8

CORC > 上海药物研究所 > 中国科学院上海药物研究所 > 药理学第一研究室

	Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana
	Yin, Xia 1,4; Feng, Tao 2; Li, Zheng-Hui 2; Leng, Ying3 ; Liu, Ji-Kai 2
刊名	Natural products and bioprospecting
	2014-06
卷号	4 期号:3 页码:149-55
ISSN号	2192-2195
DOI	10.1007/s13659-014-0020-8
文献子类	Article
英文摘要	Five new guanacastane-type diterpenes, named guanacastepenes P-T (1-5), were isolated from cultures of the fungus Psathyrella candolleana. Their structures were elucidated on the basis of extensive spectroscopic methods. All of the compounds were tested for their 11β-hydroxysteroid dehydrogenase (11β-HSD1) inhibitory activity. Compound 3 exhibited inhibitory activity against both human and mouse isozymes of 11β-HSD1 with IC50 values of 6.2 and 13.9 μM, respectively.
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/266810]
专题	药理学第一研究室
作者单位	1.University of Chinese Academy of Sciences, Beijing, 100049 People's Republic of China; 2.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China; 3.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203 People's Republic of China 4.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201 People's Republic of China ;
推荐引用方式 GB/T 7714	Yin, Xia,Feng, Tao,Li, Zheng-Hui,et al. Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana[J]. Natural products and bioprospecting,2014,4(3):149-55.
APA	Yin, Xia,Feng, Tao,Li, Zheng-Hui,Leng, Ying,&Liu, Ji-Kai.(2014).Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana.Natural products and bioprospecting,4(3),149-55.
MLA	Yin, Xia,et al."Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana".Natural products and bioprospecting 4.3(2014):149-55.