Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases | |
Liu, Yu-Ting1,4; Lin, Ze-Min2,4; He, Shi-Jun1,4; Zuo, Jian-Ping1,3,4 | |
刊名 | Life sciences |
2018-12-20 | |
ISSN号 | 1879-0631 |
DOI | 10.1016/j.lfs.2018.12.033 |
文献子类 | Article;Review |
英文摘要 | Heme oxygenase-1 (HO-1), a cellular stress protein, serves a vital metabolic function as the rate-limiting enzyme in the degradation of heme to generate carbon monoxide (CO), iron, and biliverdin (BR). HO-1 may function as one of the most momentous factors of cell adaptation to oxidase stress, as well as a regulator of inflammatory signaling programs through the generation of its biologically active end products. Intensive investigation is now focusing on the potential function of HO-1 in inflammatory disorders, among which rheumatic diseases are one of the principal issues. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/266777] |
专题 | 药理学第一研究室 |
通讯作者 | He, Shi-Jun; Zuo, Jian-Ping |
作者单位 | 1.University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China; 2.Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China; 3.Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China 4.Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China; |
推荐引用方式 GB/T 7714 | Liu, Yu-Ting,Lin, Ze-Min,He, Shi-Jun,et al. Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases[J]. Life sciences,2018. |
APA | Liu, Yu-Ting,Lin, Ze-Min,He, Shi-Jun,&Zuo, Jian-Ping.(2018).Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases.Life sciences. |
MLA | Liu, Yu-Ting,et al."Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases".Life sciences (2018). |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论