Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases
Liu, Yu-Ting1,4; Lin, Ze-Min2,4; He, Shi-Jun1,4; Zuo, Jian-Ping1,3,4
刊名Life sciences
2018-12-20
ISSN号1879-0631
DOI10.1016/j.lfs.2018.12.033
文献子类Article;Review
英文摘要Heme oxygenase-1 (HO-1), a cellular stress protein, serves a vital metabolic function as the rate-limiting enzyme in the degradation of heme to generate carbon monoxide (CO), iron, and biliverdin (BR). HO-1 may function as one of the most momentous factors of cell adaptation to oxidase stress, as well as a regulator of inflammatory signaling programs through the generation of its biologically active end products. Intensive investigation is now focusing on the potential function of HO-1 in inflammatory disorders, among which rheumatic diseases are one of the principal issues.
语种英语
内容类型期刊论文
源URL[http://119.78.100.183/handle/2S10ELR8/266777]  
专题药理学第一研究室
通讯作者He, Shi-Jun; Zuo, Jian-Ping
作者单位1.University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China;
2.Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China;
3.Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China
4.Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China;
推荐引用方式
GB/T 7714
Liu, Yu-Ting,Lin, Ze-Min,He, Shi-Jun,et al. Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases[J]. Life sciences,2018.
APA Liu, Yu-Ting,Lin, Ze-Min,He, Shi-Jun,&Zuo, Jian-Ping.(2018).Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases.Life sciences.
MLA Liu, Yu-Ting,et al."Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases".Life sciences (2018).
个性服务
查看访问统计
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。


©版权所有 ©2017 CSpace - Powered by CSpace